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Table 1 Characteristics of participants by cognitive impairment (n = 649)

From: Salivary flow rate and the risk of cognitive impairment among Korean elders: a cross-sectional study

Variable

n

Cognitive impairment

P-value

No

(n = 406)

Yes

(n = 243)

MMSE-KC score

649

27.0 ± 1.8

19.8 ± 3.3

< 0.001

Salivary flow rate (mL/min)

   

0.004

 Normal ( 0.3)

414

276 (68.0)

138 (56.8)

 

 Low (< 0.3)

235

130 (32.0)

105 (43.2)

 

 Hyposalivation (< 0.1)

97

66 (16.2)

31 (12.8)

 

Denture status

   

0.2

 Dentate

378

244 (60.1)

134 (55.1)

 

 Denture

271

162 (39.9)

109 (44.9)

 

Age (year)

649

75.8 ± 5.2

76.8 ± 5.5

0.03

Sex

   

0.17

 Male

211

140 (34.5)

71 (29.2)

 

 Female

438

266 (65.5)

172 (70.8)

Education level

   

< 0.001

 Junior school

495

287 (70.7)

208 (85.6)

 

 High school

154

119 (29.3)

35 (14.4)

Smokinga

   

0.02

 No

441

262 (64.5)

179 (73.7)

 

 Yes

208

144 (35.5)

64 (26.3)

Drinkingb

   

0.001

 No

219

118 (29.1)

101 (41.6)

 

 Yes

430

288 (70.9)

142 (58.4)

HbA1C

649

6.05 ± 0.8

6.12 ± 0.9

0.1

Diabetesc

   

0.09

 No

451

292 (71.9)

159 (65.4)

 

 Yes

198

114 (28.1)

84 (34.6)

Hypertensiond

   

0.03

 No

298

173 (42.6)

125 (51.4)

 

 Yes

351

233 (57.4)

118 (48.6)

Obesitye

   

0.01

 No

362

211 (52.0)

151 (62.1)

 

 Yes

287

195 (48.0)

92 (37.9)

  1. Data are presented as numbers (raw percentage) for categorical variables and mean ± standard deviation for continuous variables
  2. P-values were obtained by Chi-square test for categorical variables and T-test for continuous variables
  3. aSmoking: “No” refers to never smoked and “Yes” refers to past and current smoker
  4. bAlcohol intake: No refers to never drunken, and “Yes” refers to past and current drinker
  5. cDiabetes was determined as “Yes” if fasting plasma glucose > 126 mg/dL or HbA1C ≥ 6.5% or a history of diabetes
  6. dHypertension was determined as “Yes” if systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg or taking hypertension medication
  7. eObesity: Body mass index (kg/m2) ≥ 25
  8. MMSE-KC: Korean version of Mini-Mental State Examination in the Korean version of the Consortium to Establish a Registry for Alzheimer’s disease Assessment Packet (CERAD-K)