Fig. 5From: ABT-263 enhanced bacterial phagocytosis of macrophages in aged mouse through Beclin-1-dependent autophagyMolecular mechanisms schematic diagram. The diagram shows the possible molecular mechanism on how ABT-263 inducing Bcl-2/Beclin-1 complex dependent autophagy. This study found that ABT-263 induced Beclin1-dependent autophagy by preventing Bcl-2 from binding to Beclin-1, reducing the formation of Bcl-2/Beclin-1 complexBack to article page