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Table 2 Association of persistence with antiplatelets on long-term mortalitya after ischemic stroke

From: Effect of antiplatelet persistence on long-term mortality and predictors of non-persistence in ischemic stroke patients 75 years and older: a nationwide cohort study

Duration of antiplatelets

All-cause mortality

CVD mortality

Non-CVD mortality

Event No

Crude

HR

(95% CI)

p value

Adjusted HRb

(95% CI)

p value

Event No

Crude

HR

(95% CI)

p value

Adjusted HRb

(95% CI)

p value

Event No

Crude

HR

(95% CI)

p value

Adjusted HRb

(95% CI)

p value

Non-persistent

(< 6 months)

(n = 321)

173

2.35

(1.90-2.91)

0.000

2.13

(1.72-2.65)

0.000

63

2.40

(1.68-3.42)

0.000

2.26

(1.57-3.24)

0.000

110

2.33

(1.78-3.03)

0.000

2.06

(1.57-2.70)

0.000

Persistent

(≥ 6 months)

(n = 556)

168

Reference

Reference

59

Reference

Reference

109

Reference

Reference

  1. Analysis was performed using Cox proportional hazard regression model
  2. Abbreviations: CVD Cerebro-cardiovascular disease, No Number, HR Hazard ratio
  3. aMedian follow-up was 3.17 years
  4. bAdjusted for sex, age, income, residential area, type of insurance, Charlson comorbidity index, and number of prescribed medications