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Table 2 Study outcome (intention-to-treat analysis)

From: Efficacy of quetiapine for delirium prevention in hospitalized older medical patients: a randomized double-blind controlled trial

Outcome

Placebo

Quetiapine

OR or Difference (95% CI)

P-value

Delirium incidence, n (%)

5 (8.8)

8 (14.0)

OR = 1.698 (0.520–5.545)

0.381

Length of hospital stay (day), median (IQR)

5 (4, 8)

6 (4, 8)

Difference = 0.0 (−1,0)*

0.133

Admission to participation day (day), median (IQR)

1 (1, 2)

1 (1, 2)

Difference = 0.0 (0,0)*

0.838

Admission to delirium day, median (IQR)

2 (1.0,4.5)

3.5 (2.0,4.0)

Difference = 0.0 (0,0)*

0.361

Delirium duration (day), median (IQR)

3 (1.5,4.0)

4 (2.3,6.5)

Difference = 0.0 (0,0)*

0.557

Total participation (day), median (IQR)

2 (1, 4)

3 (1, 4)

Difference = 0.0 (0,0)*

0.190

ICU admission, n (%)

3 (5.3)

3 (5.3)

OR = 1.000 (0.193–5.177)

1.000

Rehospitalization within 90 days after discharge

23 (40.4)

24 (42.1)

OR = 1.075 (0.510–2.267)

0.849

Mortality, n (%)

 At 30 days

2 (3.5)

1 (1.8)

OR = 0.491 (0.043–5.573)

0.566

 At 90 days

9 (15.8)

7 (12.3)

OR = 0.747 (0.258–2.164)

0.591

  1. OR Odds Ratios, CI Confidence Interval, P P-value, QIR Interquartile range, ICU Intensive Care Unit, *Differences between medians using Hodges-Lehmann estimator