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Table 2 Association between different biomarkers and sarcopenia components in gender difference

From: Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population

  Unadjusted
β (95% CI)
R2 P Value Fully adjusted
β (95% CI)
R2 P Value
Variable Outcome variable: Hand grip strength (as a continuous variable)
Male P3NP 0.089 (− 0.504, 0.682) 0.001 0.767 0.217 (− 0.320, 0.753) 0.215 0.426
HtrA1 0.011 (−0.014, 0.037) 0.005 0.386 0.006 (− 0.018, 0.030) 0.172 0.627
Apelin −0.101 (− 0.203, 0.001) 0.023 0.052 − 0.137 (− 0.229, − 0.046) 0.250 0.003
Hsp72 − 0.113 (− 0.372, 0.147) 0.004 0.393 0.018 (− 0.222, 0.258) 0.205 0.883
Female P3NP −0.239 (− 0.907, 0.429) 0.002 0.482 −0.326 (− 0.927, 0.274) 0.214 0.285
HtrA1 0.001 (−0.014, 0.017) 0.001 0.851 0.004 (−0.010, 0.018) 0.240 0.562
Apelin 0.019 (−0.026, 0.064) 0.003 0.409 0.010 (−0.031, 0.051) 0.198 0.638
Hsp72 −0.007 (− 0.190, 0.175) 0.001 0.937 −0.102 (− 0.267, 0.064) 0.222 0.227
  Outcome variable: Skeletal muscle index (as a continuous variable)
Male P3NP 0.079 (0.004, 0.154) 0.038 0.040 0.081 (0.010, 0.153) 0.186 0.026
HtrA1 0.005 (0.001, 0.009) 0.054 0.024 0.005 (0.001, 0.009) 0.122 0.030
Apelin 0.096 (−0.035, 0.228) 0.019 0.148 0.090 (−0.040, 0.220) 0.119 0.173
Hsp72 0.004 (−0.032, 0.039) 0.001 0.842 0.004 (−0.030, 0.038) 0.123 0.834
Female P3NP −0.017 (− 0.119, 0.085) 0.001 0.743 −0.016 (− 0.117, 0.085) 0.055 0.752
HtrA1 −0.001 (− 0.005, 0.002) 0.005 0.441 −0.001 (− 0.005, 0.003) 0.050 0.554
Apelin 0.008 (−0.087, 0.103) 0.001 0.865 0.004 (−0.091, 0.099) 0.055 0.934
Hsp72 0.015 (−0.014, 0.043) 0.007 0.319 0.007 (−0.022, 0.037) 0.051 0.637
  Outcome variable: Gait speed (as a continuous variable)
Male P3NP 0.021 (−0.007, 0.048) 0.019 0.142 0.022 (−0.004, 0.049) 0.172 0.093
HtrA1 0.001 (−0.001, 0.002) 0.013 0.273 0.001 (−0.001, 0.002) 0.210 0.357
Apelin 0.032 (−0.016, 0.079) 0.016 0.191 0.017 (−0.029, 0.063) 0.156 0.468
Hsp72 −0.012 (− 0.025, 0.001) 0.030 0.062 −0.012 (− 0.024, 0.001) 0.160 0.059
Female P3NP 0.032 (−0.009, 0.073) 0.017 0.123 0.025 (−0.009, 0.060) 0.335 0.143
HtrA1 0.001 (−0.002, 0.001) 0.003 0.551 0.001 (−0.001, 0.001) 0.289 0.963
Apelin −0.010 (− 0.047, 0.026) 0.002 0.572 −0.016 (− 0.048, 0.015) 0.290 0.315
Hsp72 0.001 (−0.011, 0.012) 0.001 0.932 −0.004 (− 0.014, 0.006) 0.295 0.414
  1. Fully adjusted: adjustment for age, education, smoking history, number of chronic disease