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Table 2 Association between different biomarkers and sarcopenia components in gender difference

From: Cross-sectional associations among P3NP, HtrA, Hsp70, Apelin and sarcopenia in Taiwanese population

 

Unadjusted

β (95% CI)

R2

P Value

Fully adjusted

β (95% CI)

R2

P Value

Variable

Outcome variable: Hand grip strength (as a continuous variable)

Male

P3NP

0.089 (− 0.504, 0.682)

0.001

0.767

0.217 (− 0.320, 0.753)

0.215

0.426

HtrA1

0.011 (−0.014, 0.037)

0.005

0.386

0.006 (− 0.018, 0.030)

0.172

0.627

Apelin

−0.101 (− 0.203, 0.001)

0.023

0.052

− 0.137 (− 0.229, − 0.046)

0.250

0.003

Hsp72

− 0.113 (− 0.372, 0.147)

0.004

0.393

0.018 (− 0.222, 0.258)

0.205

0.883

Female

P3NP

−0.239 (− 0.907, 0.429)

0.002

0.482

−0.326 (− 0.927, 0.274)

0.214

0.285

HtrA1

0.001 (−0.014, 0.017)

0.001

0.851

0.004 (−0.010, 0.018)

0.240

0.562

Apelin

0.019 (−0.026, 0.064)

0.003

0.409

0.010 (−0.031, 0.051)

0.198

0.638

Hsp72

−0.007 (− 0.190, 0.175)

0.001

0.937

−0.102 (− 0.267, 0.064)

0.222

0.227

 

Outcome variable: Skeletal muscle index (as a continuous variable)

Male

P3NP

0.079 (0.004, 0.154)

0.038

0.040

0.081 (0.010, 0.153)

0.186

0.026

HtrA1

0.005 (0.001, 0.009)

0.054

0.024

0.005 (0.001, 0.009)

0.122

0.030

Apelin

0.096 (−0.035, 0.228)

0.019

0.148

0.090 (−0.040, 0.220)

0.119

0.173

Hsp72

0.004 (−0.032, 0.039)

0.001

0.842

0.004 (−0.030, 0.038)

0.123

0.834

Female

P3NP

−0.017 (− 0.119, 0.085)

0.001

0.743

−0.016 (− 0.117, 0.085)

0.055

0.752

HtrA1

−0.001 (− 0.005, 0.002)

0.005

0.441

−0.001 (− 0.005, 0.003)

0.050

0.554

Apelin

0.008 (−0.087, 0.103)

0.001

0.865

0.004 (−0.091, 0.099)

0.055

0.934

Hsp72

0.015 (−0.014, 0.043)

0.007

0.319

0.007 (−0.022, 0.037)

0.051

0.637

 

Outcome variable: Gait speed (as a continuous variable)

Male

P3NP

0.021 (−0.007, 0.048)

0.019

0.142

0.022 (−0.004, 0.049)

0.172

0.093

HtrA1

0.001 (−0.001, 0.002)

0.013

0.273

0.001 (−0.001, 0.002)

0.210

0.357

Apelin

0.032 (−0.016, 0.079)

0.016

0.191

0.017 (−0.029, 0.063)

0.156

0.468

Hsp72

−0.012 (− 0.025, 0.001)

0.030

0.062

−0.012 (− 0.024, 0.001)

0.160

0.059

Female

P3NP

0.032 (−0.009, 0.073)

0.017

0.123

0.025 (−0.009, 0.060)

0.335

0.143

HtrA1

0.001 (−0.002, 0.001)

0.003

0.551

0.001 (−0.001, 0.001)

0.289

0.963

Apelin

−0.010 (− 0.047, 0.026)

0.002

0.572

−0.016 (− 0.048, 0.015)

0.290

0.315

Hsp72

0.001 (−0.011, 0.012)

0.001

0.932

−0.004 (− 0.014, 0.006)

0.295

0.414

  1. Fully adjusted: adjustment for age, education, smoking history, number of chronic disease