Skip to main content

Table 3 Frequency of potentially inappropriate medications and drug-drug interactions

From: Epidemiology and associated factors of polypharmacy in older patients in primary care: a northern Italian cross-sectional study

Potentially inappropriate drugs according to the Beers-list [24]
Number of PIMs (total) Median (IQR) Mean ± SDa Min Max
341 (6.1% of all prescribed drugs) 0 (0 – 1) 0.6 ± 0.8 0 4
n PIMs per patient n patients % of participating patients
0 313 54.1%
1 207 35.7%
≥ 2 59 10.2%
TOTAL patients with ≥ 1 Beers-listed drug 266 45.9%
D or X b drug-drug interactions [26]
Number of DDIs (total) Median per patient (IQR) Min Max
776 1 (0 – 2) 0 8
n D or Xb interactions per patient n patients % of participating patients
0 188 32.5%
1 187 32.3%
2 103 17.8%
≥ 3 101 17.4%
TOTAL patients with ≥ 1 D or X interaction 391 67.5%
  1. PIMs Potentially inappropriate drugs, IQR Interquartile range, SD Standard deviation, Min Minimum, Max Maximum, DDIs Drug-drug interactions
  2. a As the median was 0, in this case also the mean per patient is reported to provide better comprehensibility
  3. b Drug-drug interactions: category D = consider drug modification, category X = avoid combination [26]