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Table 3 Levels and rates of change in the physical disability trajectory after diagnosis for each chronic condition

From: Disease-related disability burden: a comparison of seven chronic conditions in middle-aged and older adults

 

Fixed effect

Goodness of fit

Intercept

Linear change

Quadratic change

-2LL

Parameters

LR test △χ2 (△df)

Hypertension

Model 0

1.858 (1.615–2.101)

0.087 (0.046–0.129)

0.010 (0.009–0.012)

25,401.7

7

 

Model 1

1.028 (0.735–1.320)

0.174 (0.132–0.216)

0.007 (0.005–0.008)

24,851.0

12

550.7 (5)***

Model 2

0.441 (0.150–0.731)

0.154 (0.113–0.196)

0.006 (0.005–0.008)

24,591.9

13

259.1 (1)***

Model 3

0.271 (0.030–0.512)

0.120 (0.085–0.156)

0.004 (0.003–0.006)

21,169.2

15

3422.7 (2)***

Heart disease

Model 0

2.538 (2.223–2.853)

0.155 (0.102–0.207)

0.008 (0.006–0.010)

16,068.7

7

 

Model 1

1.358 (0.959–1.756)

0.235 (0.183–0.288)

0.004 (0.002–0.007)

15,684.4

12

384.3 (5)***

Model 2

0.425 (0.009–0.841)

0.222 (0.170–0.274)

0.004 (0.002–0.006)

15,563.0

13

121.4 (1)***

Model 3

0.558 (0.208–0.908)

0.161 (0.117–0.205)

0.003 (0.001–0.004)

13,317.3

15

2245.7 (2)***

Stroke

Model 0

8.104 (7.203–9.004)

0.203 (0.041–0.364)

0.005(−0.004–0.014)

3632.9

7

 

Model 1

5.104 (4.040–6.169)

0.288 (0.129–0.447)

0.001(− 0.007–0.010)

3510.6

12

122.3 (5)***

Model 2

4.509 (3.293–5.724)

0.289 (0.130–0.449)

0.001(−0.008–0.009)

3506.7

13

3.9 (1)*

Model 3

3.018 (1.861–4.175)

0.215 (0.054–0.376)

0.002(− 0.007–0.010)

2495.0

15

1011.7 (2)***

Diabetes

Model 0

2.887 (2.442–3.332)

0.080(−0.001–0.161)

0.014 (0.010–0.017)

9469.6

7

 

Model 1

2.209 (1.676–2.742)

0.173 (0.091–0.255)

0.009 (0.005–0.012)

9207.5

12

262.1 (5)***

Model 2

1.080 (0.517–1.643)

0.166 (0.086–0.247)

0.008 (0.004–0.011)

9102.6

13

104.9 (1)***

Model 3

0.805 (0.331–1.278)

0.105 (0.037–0.172)

0.006 (0.003–0.009)

7680.5

15

1422.1 (2)***

Cancer

Model 0

3.693 (2.880–4.506)

0.013(−0.137–0.163)

0.013 (0.007–0.020)

2554.0

7

 

Model 1

2.053 (1.079–3.027)

0.133(−0.015–0.282)

0.009 (0.002–0.016)

2467.9

12

86.1 (5)***

Model 2

1.156 (0.172–2.141)

0.088(−0.063–0.238)

0.009 (0.003–0.016)

2442.1

13

25.8 (1)***

Model 3

0.542(−0.184–1.268)

0.079(− 0.041–0.198)

0.007 (0.001–0.012)

2011.6

15

430.5 (2)***

Lung disease

Model 0

2.526 (2.100–2.953)

0.200 (0.144–0.257)

0.003 (0.002–0.005)

10,865.3

7

 

Model 1

1.336 (0.863–1.810)

0.305 (0.251–0.360)

−0.0004(−0.002–0.001)

10,486.0

12

379.3 (5)***

Model 2

0.681 (0.192–1.170)

0.291 (0.236–0.345)

−0.001(− 0.003–0.001)

10,427.1

13

58.9 (1)***

Model 3

0.366(−0.017–0.750)

0.213 (0.175–0.250)

− 0.001(− 0.002 to − 0.0003)

8713.5

15

1713.6 (2)***

Arthritis

Model 0

2.205 (1.942–2.468)

0.119 (0.077–0.161)

0.007 (0.005–0.008)

22,100.0

7

 

Model 1

1.466 (1.132–1.800)

0.226 (0.184–0.268)

0.003 (0.002–0.005)

21,496.9

12

603.1 (5)***

Model 2

0.833 (0.492–1.174)

0.204 (0.162–0.245)

0.003 (0.001–0.004)

21,353.7

13

143.2 (1)***

Model 3

0.613 (0.322–0.903)

0.183 (0.146–0.219)

0.001(−0.001–0.002)

18,683.7

15

2670.0 (2)***

  1. Scores of physical disability are the total of limitations in ADL, IADL, and mobility (range 0–17)
  2. Bold numbers and *indicate statistical significance (p < 0.05), ***indicate statistical significance (p < 0.001)
  3. Model 0: Duration after diagnosis and (duration after diagnosis)2
  4. Model 1: Model 0 + age at diagnosis (centered to 70 years old), gender, education level
  5. Model 2: Model 1 + number of comorbidities over time
  6. Model 3: Model 2 + depression status over time