Variables
|
Cohort (n = 122)
|
No sarcopenia (n = 88)
|
Sarcopenia (n = 34)
|
P value
|
---|
Age (Years)
|
67 (64–71)
|
67 (64–71)
|
68 (64–71)
|
0.943
|
Height (cm)
|
155.8 ± 6.1
|
157.0 ± 6.1
|
152.9 ± 4.9
|
0.001
|
Weight (kg)
|
81.6 (69.0–98.9)
|
77.1 (66.6–91.8)
|
92.4 (81.7–108.9)
|
0.002
|
BMI (kg/m2)
|
33.1 (29.0–40.1)
|
31.9 (28.3–35.6)
|
39.3 (34.3–45.4)
|
< 0.001
|
Waist-to-hip ratio (cm)
|
0.95 (0.87–0.10)
|
0.95 (0.88–0.99)
|
0.96 (0.84–1.0)
|
0.945
|
Body fat-mass (kg)
|
36.6 (28.2–47.6)
|
32.7 (26.0–41.9)
|
47.4 (37.7–55.9)
|
< 0.001
|
Body fat-mass (%)
|
48.6 ± 5.9
|
47.0 (43.8–50.6)
|
55.0 (51.0–57.0)
|
< 0.001
|
FFSTM (kg)
|
36.7 (32.6–41.3)
|
35.7 (32.8–41.1)
|
37.5 (32.3–42.9)
|
0.733
|
Android (%)
|
8.6 ± 1.4
|
8.6 ± 1.5
|
8.7 ± 1.5
|
0.880
|
Gynoid (%)
|
16.0 ± 2.5
|
16.1 ± 2.5
|
15.6 ± 2.2
|
0.260
|
VAT (cm2)
|
196.3 ± 74.5
|
183.4 ± 75.0
|
229.0 ± 65.0
|
0.002
|
SAT (cm2)
|
477.9 ± 138.2
|
441.2 ± 132.9
|
569.7 ± 105.6
|
< 0.001
|
VAT/SAT ratio
|
0.40 (0.32–0.48)
|
0.42 ± 0.13
|
0.40 ± 0.10
|
0.628
|
ASM (kg)
|
16.5 (14.7–19.6)
|
16.5 (14.6–19.5)
|
17.4 (15.0–20.2)
|
0.455
|
ASMI (kg/m2)
|
6.9 (6.1–7.9)
|
6.8 (6.0–7.5)
|
7.4 (6.2–8.8)
|
0.036
|
ASMBMI (kg/m2)
|
0.514 (0.459–0.578)
|
0.54 (0.50–0.67)
|
0.45 (0.42–0.48)
|
< 0.001
|
Peripheral fat (kg)
|
18.2 (14.0–23.9)
|
16.3 (13.4–20.4)
|
24.7 (19.5–28.2)
|
< 0.001
|
Peripheral fat/ASM ratio
|
1.1 ± 0.3
|
1.01 ± 0.20
|
1.36 ± 0.20
|
< 0.001
|
Functional Movement
|
Grip strength (kg)
|
19.6 ± 4.5
|
20.4 ± 4.3
|
17.6 ± 4.3
|
0.002
|
Grip strengthBMI (kg/m2)
|
0.59 ± 0.18
|
0.63 (0.55–0.76)
|
0.48 (0.39–0.53)
|
< 0.001
|
6-min walk (m)
|
450 (395–490)
|
462.5 (402.5–496.3)
|
405.0 (351.4–462.3)
|
0.010
|
Gait speed (m/sec)
|
1.53 (1.38–1.67)
|
1.55 (1.41–1.68)
|
1.46 (1.31–1.56)
|
0.022
|
3 m timed-up and go (sec)
|
6.9 (6.2–8.1)
|
6.7 (6.1–7.8)
|
7.2 (6.5–8.4)
|
0.057
|
- All normally distributed and skewed data are reported as mean ± SD and Median (IQR – 25-75th percentile). Abbreviations: BMI Body mass index, FFSTM Fat-free soft tissue mass, VAT visceral adipose tissue, SAT subcutaneous adipose tissue, ASM appendicular skeletal muscle mass, ASMI appendicular skeletal muscle mass index, ASMBMI appendicular skeletal muscle mass adjust for body mass index, Grip strengthBMI Grip strength adjusted for body mass index
- P values represent a significant difference between those with and without sarcopenia. Parametric and non-parametric (Mann-Whitney U) independent t-tests were conducted on normally distributed and skewed data, respectively