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Table 4 Adjusted a hazard ratio (95% CI) for death by age category b and the interaction of comorbidities.

From: The effect of comorbidities on survival in persons with Alzheimer’s disease: a matched cohort study

 

AD cohort

Non-AD cohort

Comorbidities

< 80 years

≥80 years

< 80 years

≥80 years

Any cardiovascular disease

1.32 (1.28–1.36)

1.25 (1.22–1.28)

1.60 (1.53–1.68)

1.52 (1.47–1.56)

Coronary artery disease

1.36 (1.32–1.41)

1.28 (1.25–1.31)

1.78 (1.69–1.87)

1.59 (1.54–1.64)

Stroke

1.45 (1.38–1.52)

1.25 (1.20–1.30)

2.27 (2.11–2.44)

1.74 (1.68–1.82)

Diabetes

1.29 (1.24–1.34)

1.19 (1.16–1.23)

1.86 (1.75–1.97)

1.52 (1.46–1.58)

Asthma/COPD

1.28 (1.22–1.34)

1.21 (1.17–1.26)

1.71 (1.61–1.83)

1.40 (1.35–1.46)

History of hip fracture

1.64 (1.51–1.79)

1.38 (1.32–1.44)

2.38 (2.09–2.72)

1.87 (1.77–1.97)

Cancer within 5 years of start of follow-up

1.53 (1.48–1.58)

1.23 (1.19–1.27)

2.94 (2.81–3.09)

1.61 (1.56–1.66)

Any mental or behavioral disorder (exc. dementia)

1.11 (1.07–1.14)

1.11 (1.09–1.39)

1.40 (1.33–1.46)

1.42 (1.38–1.46)

  1. Data presented as hazard ratios (95% CI).
  2. a Adjusted for sex and socioeconomic position
  3. b age category at the start of follow-up
  4. Abbreviations: AD, Alzheimer’s disease; CI, confidence interval; COPD, chronic obstructive pulmonary disease; exc., excluding