Lifestyle exercise attenuates immunosenescence; flow cytometry analysis

BMC Geriatrics

Table 4 Distribution of T lymphocytes phenotypes in relation to CMV serostatus (mean ± SD)

T lymphocytes absolute count [μL]	Active IgG CMV⁺ n = 30	Active IgG CMV⁻ n = 4	p level	η²	Inactive IgG CMV⁺ n = 20	Active vs. Inactive p level	η²
CD4⁺	922.4 ± 349.6	569.0 ± 356.0	0.067	0.101	846.3 ± 506.4	0.258	0.008
CD8⁺	434.5 ± 226.9	265.2 ± 164.8	0.198	0.060	446.7 ± 262.7	0.992	0.001
CD4⁺CD45RA⁺	189.0 ± 112.8	128.9 ± 120.8	0.337	0.030	108.0 ± 88.3	< 0.01	0.132
CD4⁺CD45RO⁺	518.2 ± 219.5	319.5 ± 221.0	0.099	0.083	579.8 ± 568.8	0.589	0.006
CD8⁺CD45RA⁺	247.6 ± 149.7	123.8 ± 103.9	0.118	0.074	230.1 ± 164.5	0.536	0.003
CD8⁺CD45RO⁺	192.8 ± 114.3	145.2 ± 137.1	0.453	0.018	252.7 ± 299.5	0.977	0.020
CD4/CD8	2.5 ± 1.0	2.8 ± 1.8	0.541	0.012	2.1 ± 1.0	0.294	0.023
CD4⁺CD45RA⁺/CD4⁺CD45RO⁺	0.4 ± 0.3	0.4 ± 0.2	0.777	0.000	0.3 ± 0.3	< 0.001	0.061
CD8⁺CD45RA⁺/CD8⁺CD45RO⁺	1.6 ± 1.2	1.0 ± 0.3	0.393	0.038	1.6 ± 1.7	0.350	0.000

Abbreviations: IgG CMV⁻ cytomegalovirus seronegativity, IgG CMV⁺ cytomegalovirus seropositivity. The comparison between active and inactive group concerns CMV seropositive participants. The measurements in groups are compared by the one-way ANOVA or the Mann-Whitney non-parametric test (if the normality assumption is violated)

ISSN: 1471-2318