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Table 2 Predictors of the first severe infection in MPA

From: Association between body mass index and severe infection in older adults with microscopic polyangiitis: a retrospective cohort in Japan

  Univariate model Multivariate model
HR (95% CI) P-value HR (95% CI) P-value
Age (per 10 years) 2.08
(1.16–3.67)
0.014 2.02
(1.14–3.52)
0.016
Male (vs. female) 1.11
(0.53–2.31)
0.782 1.22
(0.55–2.74)
0.624
Lung involvement 0.83
(0.38–1.84)
0.652 0.99
(0.39–5.76)
0.977
Serum creatinine (per 1.0 mg/dL) 1.10
(0.97–1.22)
0.124 1.05
(0.91–1.20)
0.504
Diabetes mellitus 1.17
(0.52–2.67)
0.703 0.77
(0.31–1.94)
0.582
mPSL pulse therapy 2.38
(1.10–5.12)
0.027 2.48
(1.07–5.76)
0.034
BMI groups
 Low BMI (<  18.5 kg/m2) 2.88
(1.35–6.16)
0.006 2.63
(1.11–6.19)
0.027
 Normal BMI (18.5–23.0 kg/m2) Reference   Reference  
 High BMI (> 23.0 kg/m2) 0.43
(0.10–1.90)
0.265 0.42
(0.09–1.93)
0.266
  1. Data are the HR, 95% CI, and P value from Cox proportional hazard regression analyses
  2. The multivariate model was adjusted for baseline characteristics, including age, sex, lung involvement, serum creatinine level, diabetes mellitus, use of mPSL pulse therapy, and BMI groups (low, normal, and high BMI). “Normal BMI” was used as the reference category
  3. Abbreviations: BMI body mass index, mPSL methylprednisolone, MPA microscopic polyangiitis, HR hazard ratio, CI confidence interval