Domain | Measure | Data from | ||
---|---|---|---|---|
IwD | Caregiver | |||
Screening | Informed Consent | X | X | |
Anamnesis (sociodemographic and general clinical data) | X | |||
Clinical Dementia Rating | X | X | ||
Primarya | Cognition | |||
Cognitive Function | ADAS-Cog | X | ||
Physical Fitness | ||||
Lower Limb Function | SPBB | X | ||
Secondarya | Cognition | |||
Cognitive Function | MMSE | X | ||
TMT | ||||
Physical Fitness | ||||
Cardiorespiratory Capacity | Modified Bruce Treadmill Test | X | ||
Physical Fitness | SFT | X | ||
Static Balance | One Leg Balance Test | X | ||
Handgrip Strength | Handgrip Dynamometer | X | ||
Body Composition and Anthropometry | ||||
Body Mass | DXA (Hologic QDR 4500, Explorer model, version 12.4) | X | ||
Total Fat-free Mass | ||||
Fat Mass | ||||
Appendicular Skeletal Mass Index | ||||
Weight | Weighting Scale | X | ||
Height | Stadiometer | X | ||
Waist and Hip Circumferences | Measuring Tape | X | ||
Quality of Life and ADL’s Functionality | ||||
Basic and instrumental ADL | Lawton & Brody IADL Scale | X | ||
Barthel Index | ||||
Quality of Life | QoL-AD | X | X | |
Behavioral and Psychological Symptoms of Dementia | ||||
Neuropsychiatric Symptoms and Caregiver Distress | NPI | X | ||
Caregiver Burden | ||||
Caregiver Well-being and Subjective Burden | CarerQol-7D | X | ||
CarerQol-Vas | ||||
Blood-based Biomarkers and Hemodynamics | ||||
Systolic and Diastolic Blood Pressure | Digital Sphygmomanometer | X | ||
Arterial Stiffness | Pulse Wave Velocity (SphygmoCor, AtCor Medical, Australia) | X | ||
TG | Concentration in blood plasma | X | ||
TC | ||||
LDL-C | ||||
HDL-C | ||||
HbA1c | HPLC | |||
BDNF | ELISA | X | ||
VEGF | ||||
CRP | ||||
sICAM-1 | ||||
sVCAM-1 | ||||
MMP-9 | ||||
IL-6, IL-8, IL-10 | ||||
TNF-alfa | CLIA | X | ||
IGF-1 | ||||
Confoundersa | Daily Physical Activity | |||
Physical Activity Levels | Accelerometer-based activity monitors GT9X+ Link (ActiGraph) | X |