|
Screening
|
Informed Consent
|
X
|
X
|
|
Anamnesis (sociodemographic and general clinical data)
| |
X
|
|
Clinical Dementia Rating
|
X
|
X
|
|
Primarya
|
Cognition
| | |
|
Cognitive Function
|
ADAS-Cog
|
X
| |
|
Physical Fitness
| | | |
|
Lower Limb Function
|
SPBB
|
X
| |
|
Secondarya
|
Cognition
| | |
|
Cognitive Function
|
MMSE
|
X
| |
|
TMT
|
|
Physical Fitness
| | | |
|
Cardiorespiratory Capacity
|
Modified Bruce Treadmill Test
|
X
| |
|
Physical Fitness
|
SFT
|
X
| |
|
Static Balance
|
One Leg Balance Test
|
X
| |
|
Handgrip Strength
|
Handgrip Dynamometer
|
X
| |
|
Body Composition and Anthropometry
| | |
|
Body Mass
|
DXA (Hologic QDR 4500, Explorer model, version 12.4)
|
X
| |
|
Total Fat-free Mass
| |
|
Fat Mass
| |
|
Appendicular Skeletal Mass Index
| |
|
Weight
|
Weighting Scale
|
X
| |
|
Height
|
Stadiometer
|
X
| |
|
Waist and Hip Circumferences
|
Measuring Tape
|
X
| |
|
Quality of Life and ADL’s Functionality
| | |
|
Basic and instrumental ADL
|
Lawton & Brody IADL Scale
| |
X
|
|
Barthel Index
| |
|
Quality of Life
|
QoL-AD
|
X
|
X
|
|
Behavioral and Psychological Symptoms of Dementia
| | |
|
Neuropsychiatric Symptoms and Caregiver Distress
|
NPI
| |
X
|
|
Caregiver Burden
| | | |
|
Caregiver Well-being and Subjective Burden
|
CarerQol-7D
| |
X
|
|
CarerQol-Vas
|
|
Blood-based Biomarkers and Hemodynamics
| | |
|
Systolic and Diastolic Blood Pressure
|
Digital Sphygmomanometer
|
X
| |
|
Arterial Stiffness
|
Pulse Wave Velocity (SphygmoCor, AtCor Medical, Australia)
|
X
| |
|
TG
|
Concentration in blood plasma
|
X
| |
|
TC
| |
|
LDL-C
| |
|
HDL-C
| |
|
HbA1c
|
HPLC
| |
|
BDNF
|
ELISA
|
X
| |
|
VEGF
| |
|
CRP
| |
|
sICAM-1
| |
|
sVCAM-1
| |
|
MMP-9
| |
|
IL-6, IL-8, IL-10
| |
|
TNF-alfa
|
CLIA
|
X
| |
|
IGF-1
| |
|
Confoundersa
|
Daily Physical Activity
| | |
|
Physical Activity Levels
|
Accelerometer-based activity monitors GT9X+ Link (ActiGraph)
|
X
| |
