ATC code | Substance | PIM list | ADE, increased risk of | Prescriptions, n | Patients’ age (years), median (IQR) | Patients, n (%) |
---|---|---|---|---|---|---|
A02BC02 | Pantoprazole | EU(7) | - C. difficile infection - hip fracture | 107,233 | 79 (74–84) | 6.947 (60.2) |
A02BC03 | Lansoprazole | EU(7) | - C. difficile infection - hip fracture | 47,291 | 80 (75–85) | 3.238 (28.0) |
N06DX02 | Ginkgo biloba | EU(7), AT | - orthostatic hypotension and fall | 31,395 | 81 (77–86) | 2.266 (19.6) |
N02AX02 | Tramadol | EU(7), AT | - CNS side effects | 28,130 | 78 (74–84) | 4.115 (35.6) |
M01AB05 | Diclofenac | EU(7), AT | - GI bleeding, ulceration, or perforation | 23,001 | 78 (73–83) | 4.399 (38.1) |
A02BC01 | Omeprazole | EU(7) | - C. difficile infection - hip fracture | 21,601 | 79 (74–85) | 1.657 (14.3) |
A02BC05 | Esomeprazole | EU(7) | - C. difficile infection - hip fracture | 20,821 | 79 (74–84) | 1.682 (14.6) |
C02CA04 | Doxazosin | EU(7) | - orthostatic hypotension - dry mouth - urinary incontinence/ impaired micturition - CNS side effects | 18,704 | 77 (73–82) | 1.133 (9.8) |
C04AD03 | Pentoxifyllin | EU(7), AT | - orthostatic hypotension and fall | 12,658 | 80 (76–85) | 1.065 (9.2) |
C02AC06 | Rilmenidine | EU(7) | - orthostatic hypotension - bradycardia - CNS side effects | 12,241 | 78 (73–83) | 919 (8.0) |