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Table 2 Frailty and Outcomes in Older Patients Hospitalized with Pneumonia

From: Frailty and hospitalization-associated disability after pneumonia: A prospective cohort study

Outcomes

Number of Outcome Events (%) and OR (95% CI)a

P value

Total

Robust

Pre-frailty

Mild-to-moderate frailty

Severe frailty

Primary Outcome

ā€ƒDeath or functional decline at 30 daysb

99 (67.4)

21 (46.7)

22 (61.1)

31 (83.8)

25 (86.2)

<0.001

NA

Reference

1.46 (0.58-3.69)

3.95 (1.31-11.89)

5.34 (1.54-18.49)

0.014

Secondary patient outcomes

ā€ƒDeath at 30 days

19 (10.8)

3 (6.7)

1 (2.8)

6 (16.2)

9 (15.5)

0.129

NA

Reference

0.38 (0.37-3.84)

2.36 (0.51-10.94)

2.27 (0.54-9.62)

0.281

ā€ƒFunctional decline at 30 daysb

84 (63.6)

18 (42.9)

21 (60.0)

25 (80.7)

20 (83.3)

0.001

NA

Reference

1.63 (0.63-4.20)

3.84 (1.24-11.86)

5.33 (1.50-19.02)

0.022

Secondary process outcomes

ā€ƒIntensive care unit stay

38 (21.8)

4 (8.9)

8 (22.2)

9 (24.3)

17 (30.4)

0.074

NA

Reference

2.51 (0.67-9.44)

2.44 (0.64-9.27)

3.15 (0.92-10.73)

0.336

ā€ƒPsychoactive drug usec

41 (26.5)

10 (22.2)

7 (22.6)

13 (41.9)

11 (22.9)

0.189

NA

Reference

0.88 (0.28-2.78)

1.92 (0.64-5.78)

0.66 (0.22-1.96)

0.236

ā€ƒNasogastric tube feeding

50 (28.4)

3 (6.7)

5 (13.9)

7 (18.9)

35 (60.3)

<0.001

NA

Reference

1.97 (0.42-9.22)

2.50 (0.56-11.22)

17.08 (4.49-64.99)

<0.001

ā€ƒProlonged hospitalization (ā‰„15 days)

62 (35.6)

8 (18.2)

14 (38.9)

11 (29.7)

29 (50.9)

0.006

NA

Reference

2.72 (0.95-7.82)

1.58 (0.52-4.80)

3.72 (1.38-9.98)

0.039

ā€ƒDischarge to a long-term care institutiond

39 (27.7)

2 (4.4)

7 (20.0)

14 (41.2)

16 (59.3)

<0.001

NA

Reference

4.56 (0.83-24.87)

9.79 (1.88-51.00)

25.11 (4.70-134.07)

<0.001

  1. Abbreviations: CI confidence interval, NA not applicable, OR odds ratio
  2. aAdjusted for age, sex, and CURB-65 score
  3. bAssessed for 147 patients who did not have the maximum disability on admission
  4. cAssessed for 155 patients who were not receiving psychoactive drugs on admission
  5. dAssessed for 141 patients who were not admitted from a nursing home