Table 1 Clinical characteristics of study participants classified by HTPR
Variables | HTPR group (N = 76) | non-HTPR group (N = 228) | p value |
|---|---|---|---|
Age, years | 79 ± 7 | 76 ± 8 | 0.008 |
Male sex, n (%) | 54 (71.1) | 179 (78.5) | 0.183 |
Body mass index, kg/m2 | 24.0 ± 2.7 | 24.6 ± 3.1 | 0.149 |
Systolic blood pressure, mmHg | 138 ± 18 | 134 ± 16 | 0.076 |
Diastolic blood pressure, mmHg | 71 ± 11 | 73 ± 11 | 0.164 |
Medical history | |||
Coronary heart disease, n (%) | 59 (77.6) | 210 (92.1) | 0.001 |
PCI, n (%) | 33 (43.4) | 115 (50.4) | 0.289 |
Ischemic stroke or TIA, n (%) | 39 (51.3) | 56 (24.6) | < 0.001 |
Peripheral artery stenosis, n (%) | 7 (9.2) | 29 (12.7) | 0.412 |
Hypertension, n (%) | 63 (80.8) | 175 (75.1) | 0.307 |
Diabetes mellitus, n (%) | 24 (31.6) | 75 (32.9) | 0.832 |
Hyperlipidemia, n (%) | 69 (90.8) | 191 (83.8) | 0.132 |
Smoking habits: former/current, n (%) | 17/8 (22.4/10.5) | 66/25 (28.9/11.0) | 0.505 |
Alcoholic habits: former/current, n (%) | 5/5 (6.5/6.5) | 22/28 (9.6/12.3) | 0.239 |
Daily aspirin dose | |||
100 mg, n (%) | 65 (85.5) | 196 (86.0) | 0.924 |
50 mg or 75 mg, n (%) | 11 (14.5) | 32 (14.0) | |
Medications taken | |||
ACEIs/ARBs, n (%) | 48 (63.2) | 114 (50.0) | 0.046 |
Calcium-channel blockers, n (%) | 24 (31.6) | 85 (37.3) | 0.369 |
β-blockers, n (%) | 53 (69.7) | 146 (64.0) | 0.365 |
Nitrates, n (%) | 31 (40.8) | 68 (29.8) | 0.077 |
Statins, n (%) | 72 (94.7) | 202 (88.6) | 0.120 |
Diuretics, n (%) | 11 (14.5) | 33 (14.5) | 0.999 |
Proton pump inhibitors, n (%) | 21 (27.6) | 41 (18.0) | 0.071 |