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Table 2 Multivariable linear regressions for ZBI scores of different models

From: Predictors of caregiver burden in aged caregivers of demented older patients

 

Model 1

Model 2 (NPI_severity_total)

Model 3(NPI_severity)

β(95% C.I)

P value

β(95% C.I)

P value

β(95% C.I)

P value

Pt_Age

−0.34 (− 0.72 to 0.04)

0.080

−0.34 (− 0.71 to 0.02)

0.066

−0.27 (− 0.63 to 0.10)

0.151

Pt_Sex, Male

2.25 (−5.26 to 9.77)

0.555

0.47 (−6.75 to 7.69)

0.899

0.45 (− 6.76 to 7.67)

0.902

Pt_Education, yr

−0.33 (− 0.86 to 0.21)

0.232

− 0.34 (− 0.86 to 0.17)

0.185

−0.37 (− 0.88 to 0.14)

0.157

Caregiver_Age

−0.23 (− 0.62 to 0.16)

0.253

−0.15 (− 0.53 to 0.22)

0.417

−0.24 (− 0.62 to 0.14)

0.211

Caregiver_Sex, Male

−4.99 (− 13.06 to 3.08)

0.225

− 6.58 (− 14.32 to 1.16)

0.095

− 5.62 (− 13.35 to 2.11)

0.153

Caregiver_Education,yr

0.47 (− 0.07 to 1.02)

0.088

0.39 (− 0.13 to 0.92)

0.141

0.32 (− 0.21 to 0.85)

0.241

Relasionship

 Spouse

0.00 (reference)

 

0.00 (reference)

 

0.00 (reference)

 

 Offspring

7.08 (−4.46 to 18.61)

0.228

6.69 (−4.35 to 17.73)

0.234

4.19 (−6.92 to 15.29)

0.459

 Others

−5.80 (−16.91 to 5.30)

0.305

−7.79 (− 18.44 to 2.87)

0.151

−7.44 (− 18.17 to 3.30)

0.174

Live together, yes

7.25 (− 1.30 to 15.80)

0.096

4.81 (−3.42 to 13.05)

0.251

3.80 (−4.47 to 12.08)

0.367

Family income

 < 30,000 NTD

0.00 (reference)

 

0.00 (reference)

 

0.00 (reference)

 

 30,000 ~ 100,000 NTD

2.05 (− 2.35 to 6.46)

0.360

2.38 (−1.84 to 6.60)

0.268

2.34 (−1.84 to 6.53)

0.271

 > 100,000 NTD

−9.54 (−17.02 to − 2.06)

0.013*

−9.29 (− 16.45 to − 2.14)

0.011*

−8.99 (− 16.08 to − 1.90)

0.013*

MMSE

−0.22 (− 0.65 to 0.22)

0.329

− 0.22 (− 0.64 to 0.19)

0.294

− 0.28 (− 0.70 to 0.14)

0.185

CDR

− 0.75 (−4.47 to 2.97)

0.692

− 2.81 (− 6.45 to 0.83)

0.130

−3.91 (−7.62 to − 0.20

0.039*

IADL

0.96 (0.50 to 1.41)

< 0.001*

0.94 (0.51 to 1.38)

< 0.001*

1.00 (0.55 to 1.45)

< 0.001*

Drinking, yes

−5.18 (− 17.57 to 7.21)

0.411

−3.36 (− 15.23 to 8.51)

0.578

−4.13 (− 15.87 to 7.61)

0.489

Smoking,yes

− 0.84 (− 8.18 to 6.51)

0.823

−1.26 (− 8.29 to 5.77)

0.725

− 0.30 (−7.43 to 6.83)

0.934

Physical activity in 7 days

 Vigorous activities,yes

0.63 (−6.60 to 7.87)

0.863

0.71 (−6.21 to 7.63)

0.840

1.58 (− 5.38 to 8.53)

0.656

 Moderate activities,yes

−3.20 (−8.67 to 2.27)

0.251

−1.69 (−6.95 to 3.58)

0.528

−1.25 (−6.49 to 4.00)

0.640

 Walking,yes

1.23 (−3.68 to 6.14)

0.622

2.29 (−2.43 to 7.00)

0.341

1.30 (−3.52 to 6.13)

0.595

 Sitting,yes

7.94 (−26.57 to 42.44)

0.651

−1.75 (−34.95 to 31.45)

0.917

2.65 (−30.83 to 36.13)

0.876

Physical diseases

 Hypertension

−1.75 (−5.90 to 2.40)

0.407

−1.03 (− 5.01 to 2.95)

0.611

−1.79 (− 5.76 to 2.18)

0.375

 Diabetes

0.87 (−3.50 to 5.23)

0.696

1.52 (−2.67 to 5.70)

0.476

1.93 (−2.32 to 6.19)

0.371

 Hyperlipidemia

−0.06 (−4.77 to 4.64)

0.979

0.82 (−3.69 to 5.34)

0.719

0.37 (−4.13 to 4.86)

0.872

 Ischemic stroke

0.22 (−6.71 to 7.15)

0.951

0.01 (− 6.62 to 6.64)

0.998

−0.42 (−7.05 to 6.20)

0.900

 Hemorrhagic stroke

0.03 (−10.16 to 10.22)

0.995

0.69 (−9.06 to 10.44)

0.889

−1.05 (− 10.76 to 8.66)

0.831

 Transient Ischemic Attack

1.09 (−5.71 to 7.88)

0.753

0.91 (−5.59 to 7.42)

0.782

1.38 (−5.08 to 7.83)

0.675

 Head trauma

4.01 (−4.81 to 12.84)

0.371

1.44 (−7.05 to 9.94)

0.738

−0.97 (−9.71 to 7.77)

0.828

 CAD

2.58 (−6.35 to 11.52)

0.570

1.94 (−6.62 to 10.49)

0.656

2.89 (−5.84 to 11.61)

0.516

 Heart failure

−3.76 (−17.79 to 10.27)

0.599

−2.59 (−16.02 to 10.84)

0.704

−5.97 (− 19.40 to 7.46)

0.382

 MDD

−1.34 (− 13.32 to 10.65)

0.826

−5.62 (− 17.20 to 5.95)

0.340

−6.08 (− 17.90 to 5.73)

0.312

 Anxiety

6.54 (−3.58 to 16.66)

0.205

3.37 (−6.38 to 13.13)

0.496

5.32 (−5.12 to 15.75)

0.317

 NPI_Total

  

1.09 (0.69 to 1.49)

< 0.001*

N/A

 

 NPI_Delusion

    

1.26 (−1.57 to 4.10)

0.380

 NPI_Hallucination

    

−2.03 (−5.21 to 1.15)

0.211

 NPI_Agitation

    

0.99 (−2.09 to 4.08)

0.526

 NPI_Depression

    

−3.03 (−6.00 to −0.06)

0.046*

 NPI_Anxiety

    

2.84 (−0.16 to 5.84)

0.063

 NPI_Euphoria

    

5.82 (−0.28 to 11.91)

0.061

 NPI_Apathy

    

3.70 (1.47 to 5.93)

0.001*

 NPI_Disinhibition

    

0.63 (−2.83 to 4.09)

0.721

 NPI_Irritability

    

3.33 (0.30 to 6.36)

0.031*

 NPI_Aberrant motor acitivity

    

−0.83 (−4.35 to 2.70)

0.644

 NPI_Night

    

1.25 (−0.72 to 3.22)

0.214

 NPI_Appetite

    

1.97 (−0.76 to 4.69)

0.157

  1. Abbreviations: NTD new Taiwan dollar, MMSE mini-mental state examination, CDR clinical dementia rating Scale, IADL instrumental activities of daily living, CAD coronary artery disease, MDD major depressive disorder
  2. *p < 0.05