Table 5 Independent ICH^a risk factors for the entire CCP^b population and by sex

HAS-BLED score ≥ 3

3.5 (1.9–6.7)

4.2 (1.7–10.7)

2.9 (1.2–7.1)

Hypercholesterolemia

1.6 (1.1–2.4)

2.1 (1.2–3.5)

1.2 (0.7–2.1)

Cardiovascular disease*

1.5 (1.1–2.1)

1.1 (0.6–1.7)

2.2 (1.3–3.6)

Statins

0.6 (0.4–0.9)

0.6 (0.4–1.0)

0.6 (0.3–1.1)

Heart failure

0.6 (0.4–0.9)

0.7 (0.4–1.1)

0.5 (0.3–1.0)

NOAC^d

0.5 (0.1–1.6)

0.2 (0.0–1.6)

0.9 (0.2–3.9)

VKA^c

1.2 (0.9–1.7)

1.6 (1.0–2.6)

0.9 (0.5–1.6)

Falls (background)

0.9 (0.5–1.4)

0.9 (0.5–1.5)

0.7 (0.3–1.9)

Age ≥ 80 years

1.3 (0.9–2.1)

2.3 (1.2–4.6)

0.9 (0.6–1.6)

Diabetes

0.7 (0.5–1.0)

0.6 (0.4–1.0)

0.9 (0.5–1.5)