Table 1 Baseline characteristics by frailty status
|  | All patients (n = 198) | Not frail (CFS 1–4) (n = 158) | Frail (CFS 5–9) (n = 40) |
|---|---|---|---|
Age, years (mean, SD) | 79 (6) | 78 (6) | 83 (7) |
Male | 115 (58) | 99 (63) | 16 (40) |
Primary diagnosis | |||
 Non-ST segment elevation myocardial infarction | 151 (76) | 122 (77) | 29 (73) |
 ST-segment elevation myocardial infarction | 47 (24) | 36 (23) | 11 (28) |
Past medical history | |||
 Heart failure | 36 (18) | 21 (13) | 15 (38) |
 Stroke | 35 (18) | 25 (16) | 10 (25) |
 Diabetes mellitus | 35 (18) | 32 (20) | 3 (8) |
 Chronic kidney disease (stage III or worse) | 45 (23) | 30 (19) | 15 (38) |
 Peripheral vascular disease | 28 (14) | 21 (13) | 7 (18) |
 Chronic respiratory disease | 39 (20) | 25 (16) | 14 (35) |
 Dementia | 14 (7) | 7 (4) | 7 (18) |
 Current or ex-smoker | 118 (60) | 96 (61) | 22 (55) |
Medications at recruitment | |||
 Total number prescribed drugs (mean, SD) | 9.2 (3.1) | 8.9 (3.1) | 10.5 (2.9) |
 Aspirin | 178 (90) | 144 (91) | 34 (85) |
 Clopidogrel | 183 (92) | 145 (92) | 38 (95) |
 ACE-inhibitor or ARB | 127 (64) | 113 (72) | 14 (35) |
 Diuretic | 80 (40) | 57 (36) | 23 (58) |
 Beta-blocker | 118 (60) | 98 (62) | 20 (50) |
 Statin | 155 (78) | 132 (84) | 23 (58) |
 Oral anticoagulant | 26 (13) | 22 (14) | 4 (10) |
Laboratory measures | |||
 Haemoglobin, g/L (mean, SD) | 13.1 (1.8) | 13.1 (1.8) | 12.7 (2.0) |
 Creatinine, μmol/L (mean, SD) | 104 (45) | 101 (39) | 119 (62) |
 Estimated GFR, ml/min/1.73 m2 (mean, SD) | 62 (24) | 65 (23) | 54 (24) |
Risk and functional measures | |||
 GRACE 2 12-month mortality (mean, SD) | 18.5 (13.2) | 16.2 (11.7) | 27.8 (15.0) |
 Charlson comorbidity index (mean, SD) | 2.9 (1.8) | 2.6 (1.6) | 3.9 (2.2) |
 Karnofsky scale score (mean, SD) | 78.5 (17.1) | 84.6 (11.8) | 54.5 (13.0) |