Table 1 Characteristics of the population, overall and acGEIcording to the number of medications taken daily
Overall population | Tertile groups of number of drug prescriptions daily | |||
|---|---|---|---|---|
Tertile 1 | Tertile 2 | Tertile 3 | ||
Number of patients | 556 patients | 155 (28%) | 210 (38%) | 191 (34%) |
Number of daily drug prescriptions: n [IQR], (range) | 6.0 [5.0; 7.0], (2–7) | 9.0 [8.0; 10.0], (8–10) | 12.0 [11.0; 13.0], (11–24) | |
Patients’ characteristics | ||||
Age (year): Mean ± SD | 82.5 ± 4.8 | 82.6 ± 5.0 | 82.6 ± 4.6 | 82.2 ± 4.9 |
Male | 318 (57%) | 94 (61%) | 115 (55%) | 109 (57%) |
Blood pressure (mmHg) | ||||
SBP Median [IQ] | 142.0 [130.0;160.0] | 140.0 [130.0; 160.0] | 142.0 [130.0; 159.0] | 143.5 [130.0; 160.0] |
DBP Median [IQ] | 73.5 [69.0; 80.0] | 73.0 [69.0; 80.0] | 75.0 [70.0; 80.0] | 72.0 [68.0; 80.0] |
Body mass index (BMI): (kg/m2) | 26.5 ± 5.0 | 25.7 ± 4.8 | 26.3 ± 4.9 | 27.3 ± 5.1a |
Diabetes | 219 (39%) | 53 (34%) | 68 (32%) | 98 (51%)b |
Chronic heart failure | 194 (35%) | 52 (34%) | 65 (31%) | 77 (40%) |
Chronic respiratory disease | 62 (11%) | 16 (10%) | 17 (8%) | 29 (15%) |
Peripheral vascular disease | 138 (25%) | 39 (25%) | 48 (23%) | 51 (27%) |
Cerebrovascular disease | 75 (13%) | 22 (14%) | 25 (12%) | 28 (15%) |
Dysrhythmia | 155 (28%) | 35 (23%) | 61 (29%) | 59 (31%) |
Active malignancy | 55 (10%) | 16 (10%) | 20 (10%) | 19 (10%) |
Behavioral disorders | 53 (10%) | 19 (12%) | 19 (9%) | 15 (8%) |
Residence: independently at home | 508 (91%) | 141 (91%) | 195 (93%) | 172 (90%) |
Mobility: walks unassisted | 499 (90%) | 136 (88%) | 190 (90%) | 173 (91%) |
Hemoglobin (g/dl) median [IQ] | 11.4 [10.4; 12.4] | 11.3 [10.2; 12.4] | 11.5 [10.5; 12.3] | 11.3 [10.4; 12.4] |
eGFR (CG) (ml/min) Median [IQ] | 13.0 [10.1; 15.4] | 25.0 [16.8; 30.9] | 23.9 [19.0; 30.4] | 25.2 [18.4; 30.1] |
eGFR (MDRD) (ml/min/1.73 m2) Median [IQ] | 14.2 [11.1; 16.7] | 14.3 [10.9; 16.7] | 14.4 [11.3; 17.1] | 13.8 [10.9; 16.5] |
Proteinuria (g/g): n(%) | ||||
< 0.5 | 174 (31%) | 45 (29%) | 78 (37%) | 51 (27%) |
[0.5–1 | 105 (19%) | 40 (26%) | 40 (19%) | 25 (13%) |
≥ 1 | 212 (38%) | 57 (37%) | 70 (33%) | 85 (45%) |
Miss | 65 (12%) | 13 (8%) | 22 (10%) | 30 (16%)a |
Nephropathy | ||||
Vascular | 204 (37%) | 49 (32%) | 93 (44%) | 62 (32%)a |
Diabetic | 135 (24%) | 31 (20%) | 37 (18%) | 67 (35%) |
Undetermined | 99 (18%) | 32 (21%) | 37 (18%) | 30 (16%) |
Glomerulopathy | 57 (10%) | 17 (11%) | 25 (12%) | 15 (8%) |
Tubulointerstitial | 61 (11%) | 26 (17%) | 18 (9%) | 17 (9%) |