Table 2 Concomitant non-OAB medications relevant to cognition during double-blind treatment period
n (%) | Placebo (n = 442) | Mirabegron Total (n = 445) |
|---|---|---|
CONCOMITANT ANTIDEPRESSANTS | ||
 SSRIs | 54 (12.2) | 53 (11.9) |
  Citalopram | 14 (3.2) | 9 (2.0) |
  Sertraline | 11 (2.5) | 4 (0.9) |
  Escitalopram oxalate | 5 (1.1) | 8 (1.8) |
  Escitalopram | 5 (1.1) | 7 (1.6) |
  Fluoxetine | 8 (1.8) | 4 (0.9) |
  Citalopram hydrobromide | 3 (0.7) | 6 (1.3) |
  Paroxetine | 1 (0.2) | 6 (1.3) |
  Sertraline hydrochloride | 4 (0.9) | 3 (0.7) |
  Fluoxetine hydrochloride | 3 (0.7) | 3 (0.7) |
  Paroxetine hydrochloride | 0 | 3 (0.7) |
 Other antidepressants | 23 (5.2) | 31 (7.0) |
  Trazodone | 13 (2.9) | 17 (3.8) |
  Duloxetine | 3 (0.7) | 4 (0.9) |
  Duloxetine hydrochloride | 4 (0.9) | 2 (0.4) |
  Mirtazapine | 2 (0.5) | 3 (0.7) |
  Trazodone hydrochloride | 0 | 3 (0.7) |
  Venlafaxine hydrochloride | 2 (0.5) | 1 (0.2) |
  Desvenlafaxine succinate | 0 | 1 (0.2) |
  Nefazodone | 0 | 1 (0.2) |
  Oxitriptan | 0 | 1 (0.2) |
  Venlafaxine | 1 (0.2) | 0 |
  Vortioxetine | 1 (0.2) | 0 |
 Non-selective monoamine reuptake inhibitors | 7 (1.6) | 9 (2.0) |
  Amitriptyline | 2 (0.5) | 7 (1.6) |
  Doxepin | 1 (0.2) | 1 (0.2) |
  Nortriptyline | 2 (0.5) | 0 |
  Amitriptyline hydrochloride | 0 | 1 (0.2) |
  Imipramine | 1 (0.2) | 0 |
  Nortriptyline hydrochloride | 1 (0.2) | 0 |
 Diazepines, oxazepines, thiazepines and oxepines | 3 (0.7) | 1 (0.2) |
  Quetiapine fumarate | 3 (0.7) | 1 (0.2) |
 Other antipsychotics | 0 | 2 (0.4) |
  Aripiprazole | 0 | 1 (0.2) |
  Risperidone | 0 | 1 (0.2) |
CONCOMITANT ANTICHOLINERGICS | ||
 Antihistamines for systemic use | 38 (8.6) | 41 (9.2) |
  Hydroxyzine | 2 (0.5) | 2 (0.4) |
  Hydroxyzine hydrochloride | 1 (0.2) | 1 (0.2) |
 Aminoalkyl ethers | 15 (3.4) | 16 (3.6) |
  Diphenhydramine hydrochloride | 10 (2.3) | 11 (2.5) |
  Diphenhydramine | 4 (0.9) | 4 (0.9) |
  Dimenhydrinate | 1 (0.2) | 1 (0.2) |
  Carbinoxamine maleate | 0 | 1 (0.2) |
 Piperazine derivatives | 3 (0.7) | 2 (0.4) |
  Meclozine | 2 (0.5) | 1 (0.2) |
 Phenothiazine derivatives | 1 (0.2) | 1 (0.2) |
  Promethazine | 1 (0.2) | 0 |
  Promethazine hydrochloride | 0 | 1 (0.2) |
 Substituted alkylamines | 0 | 2 (0.4) |
  Chlorphenamine maleate | 0 | 2 (0.4) |
 Cough and cold preparations | 17 (3.8) | 20 (4.5) |
  Promethazine with codeine | 0 | 1 (0.2) |
 Carbamic acid esters | 5 (1.1) | 1 (0.2) |
  Carisoprodol | 2 (0.5) | 1 (0.2) |
 Synthetic anticholinergics, esters with tertiary amine groups | 0 | 2 (0.4) |
  Dicycloverine hydrochloride | 0 | 2 (0.4) |