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Table 7 Illustrative sample size calculations; transition from baseline prefrail status; 2 year follow up

From: Developing a composite outcome measure for frailty prevention trials – rationale, derivation and sample size comparison with other candidate measures

To detect relative risk reduction of:Transition to frail (per group)Transition to frail/dead/too ill (per group)Ordinal (robust vs prefrail vs non frail/dead/too ill (per group)
20%3621815177
25%2389558117
30%157636087
40%85319755
50%52012338
  1. All two-sided, alpha 0.05, power 0.90
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