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Table 1 Derivation of frailty score components in ELSA

From: Developing a composite outcome measure for frailty prevention trials – rationale, derivation and sample size comparison with other candidate measures

ComponentDefinition
Weight lossBMI < 18.5 kg/m2 OR > 10% weight loss since last wave
ExhaustionPositive answer to either CES-D question (‘everything I did was an effort’ or ‘I could not get going’
Low grip strength (adjusted for BMI)
Males: Grip adjusted for BMI = Maximum grip – ((BMI-27.6)× 0.31)
Females: Grip adjusted for BMI = Maximum grip – ((BMI-27.9)× 0.07)
Low grip strength was defined as values in the lowest quintile at wave 2, for males and females separately:
M < 31.12 kg
F < 17.60 kg
Low gait speed (adjusted for height)
Males: Gait speed adjusted for BMI = Gait speed – ((height-172)×0.00941)
Females: Gait speed adjusted for BMI = Gait speed – ((height-158)× 0.010)
Low gait speed was defined as values in the lowest quintile at wave 2, for males and females separately.
M < 0.691 m/s
F < 0.619 m/s
Low activityM < 16.5 activity units
F < 13.5 activity units
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