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Table 6 Evidence profile of quality of life of institutionalized and non-institutionalized elderly for LEIPAD questionnaire

From: Does the institutionalization influence elderly’s quality of life? A systematic review and meta–analysis

Certainty assessment

Summary of findings

№ of participants (studies) Follow-up

Risk of bias

Inconsistency

Indirectness

Imprecision

Publication bias

Overall certainty of evidence

Study event rates (%)

Anticipated absolute effects

With NIE

With IE

Risk with NIE

Risk difference with IE

LEIPAD – Overall

 1765 (2 observational studies)

very serious a

very serious b,c

not serious

not serious

very strong association

all plausible residual confounding would suggest spurious effect, while no effect was observed

VERY LOW

1009

756

SMD 0.11 higher (0.1 lower to 0.32 higher)

LEIPAD - Physical functions

 280 (2 observational studies)

very serious a

not serious

not serious

serious d

very strong association

all plausible residual confounding would suggest spurious effect, while no effect was observed

LOW

161

119

SMD 0.14 higher (0.1 lower to 0.38 higher)

LEIPAD - Self-care skills

 280 (2 observational studies)

very serious a

very serious b,c

not serious

very serious d, e

very strong association

all plausible residual confounding would suggest spurious effect, while no effect was observed

VERY LOW

161

119

SMD 0.15 higher (0.47 lower to 0.77 higher)

LEIPAD - Cognitive functions

 280 (2 observational studies)

very serious a

not serious

not serious

serious d

strong association

all plausible residual confounding would suggest spurious effect, while no effect was observed

VERY LOW

161

119

SMD 0.26

lower (0.5 lower to 0.02 lower)

LEIPAD - Depression and anxiety

 280 (2 observational studies)

very serious a

not serious

not serious

serious d

strong association

all plausible residual confounding would suggest spurious effect, while no effect was observed

VERY LOW

161

119

SMD 0.24

lower (0.48 lower to 0)

LEIPAD - Social functions

 280 (2 observational studies)

very serious a

not serious

not serious

serious d

strong association

all plausible residual confounding would suggest spurious effect, while no effect was observed

VERY LOW

161

119

SMD 0.35 SD higher (0.11 higher to 0.59 higher)

LEIPAD - Sexual functions

 280 (2 observational studies)

very serious a

not serious

not serious

serious d

all plausible residual confounding would suggest spurious effect, while no effect was observed

VERY LOW

161

119

SMD 0.78 higher (0.5 higher to 1.06 higher)

LEIPAD - Life Satisfaction

 85 (2 observational studies)

very serious a

not serious

not serious

serious d

very strong association

all plausible residual confounding would suggest spurious effect, while no effect was observed

LOW

43

42

SMD 0.06 higher (0.37 lower to 0.48 higher)

  1. Notes: SMD Standard mean difference; a Only studies with some risk of bias were included in this analysis; b Considerable heterogeneity; c There is wide variation in the effect estimates across studies with little or no overlap of confidence intervals associated with the effect estimates; d Total number of participants is less than 400; e Upper and lower confidence limit crosses the effect size were greater than 0.5