Table 1 Patients and tumor characteristics. The Chi-square test was used for analysis of categorical variables. The § indicates when Fisher's exact test was used. The Student’s t-test was performed for continuous variables. A P-value <0.05 (marked with *) was considered to be statistically significant

Variables

All (%)n = 151

Group A (%) n = 79

Group B (%)n = 72

Pearson’s Chi-Square(df)

Cramer’s V

P-value

Sex

0.47 (1)

0.06

0.49

 Female

46 (30)

26 (33)

20 (28)

 Male

105 (70)

53 (67)

52 (72)

ASA

3.91 (1)

0.16

0.05

 ≥3

65 (57)

28 (35)

37 (51)

Comorbidities

 Diabetes mellitus

22 (15)

6 (8)

16 (22)

6.48 (1)

0.21

0.02*

 Coronary heart disease

68 (45)

26 (33)

42 (58)

9.84 (1)

0.26

0.002*

 Hypertension

57 (38)

23 (29)

34 (47)

5.26 (1)

0.19

0.022*

 COPD

6 (4)

5 (6)

1 (1)

2.41 (1)

0.13

0.12

Renal function (CKD stage) at T₀(for patients undergoing reversal)

27.7 (3)

0.49

<0.001*

 G1

63 (54)

46 (77)

17 (30)

 G2

45 (39)

14 (23)

31 (55)

 G3

7 (6)

0

7 (13)

 G4

1 (.9)

0

1 (2)

UICC stage n = 4 missing

6.26 (4)

0.21

0.18

 0

19 (13)

11 (14)

8 (12)

 I

44 (30)

17 (22)

27 (39)

 II

18 (12)

12 (15)

6 (9)

 III

39 (27)

21 (27)

18 (26)

 IV

27 (18)

17 (22)

10 (15)

Neoadjuvant Chemotherapy

0.60 (1)

0.06

0.44

 Yes

95 (63)

52 (66)

43 (60)

Neoadjuvant radiotherapy

1.37 (1)

0.10

0.24

 Yes

92 (63)

51 (67)

41 (58)

Adjuvant Chemotherapy

10.24 (1)

0.26

0.001*

 Yes

60 (40)

41 (52)

19 (26)

All (mean, SD)

Group A (mean, SD)

Group B (mean, SD)

F-ratio

P-value

Age in years

62 (11)

54 (8)

71 (6)

243

<0.001*

Creatinine at T₀(mg/dl)

0.86 (0.26)

0.80 (0.16)

0.93 (0.33)

8.48

0.04*

eGFR at T₀ (ml/min/1.73m²)

88.38 (17.0)

97.14 (11.94)

78.87 (16.63)

48.75

<0.001*

Serum Potassium at T₀mmol/l

4.17 (0.39)

4.18 (0.39)

4.17 (0.39)

0.03

0.88