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Table 4 Comparison of crude percentages of general practitioners (GPs) reporting to deprescribe the medications in the case vignettes, sorted by medication type, history of cardiovascular disease (CVD), and dependency level (N = 1,706)

From: General practitioners’ deprescribing decisions in older adults with polypharmacy: a case vignette study in 31 countries

Medication Level of dependency in activities of daily living
Low
(case vignette 1)
Medium
(case vignette 2)
High
(case vignette 3)
Percentage of GPs (95% CI) Percentage of GPs (95% CI) Percentage of GPs (95% CI)
Pain medications
Tramadol 50 mg, twice daily
  Without history of CVD 63.5% (61.1 to 65.9) 69.4% (67.0 to 71.7) 68.5% (66.0 to 70.9)
  With history of CVD 57.3% (55.2 to 60.2) 67.0% (64.5 to 69.4) 67.6% (65.2 to 70.1)
Paracetamol 1 g, three times daily
  Without history of CVD 47.5% (45.0 to 50.0) 41.9% (39.4 to 44.5) 44.9% (42.3 to 47.5)
  With history of CVD 43.8% (41.3 to 46.3) 40.8% (38.3 to 43.4) 43.6% (41.0 to 46.2)
Proton-pump inhibitor
Pantoprazole 20 mg, once daily
  Without history of CVD 64.5% (63.0 to 67.8) 64.4% (61.9 to 66.8) 67.8% (65.3 to 70.2)
  With history of CVD 47.1% (44.6 to 49.6) 49.0% (46.4 to 51.6) 55.6% (53.0 to 58.2)
Antihypertensive medications
Amlodipine 5 mg, once daily
  Without history of CVD 15.2% (13.4 to 17.0) 18.9% (17.0 to 21.0) 33.9% (31.4 to 36.4)
  With history of CVD 8.7% (7.3 to 10.2) 15.1% (13.3 to 17.1) 30.3% (27.9 to 32.8)
Enalapril 10 mg, once daily
  Without history of CVD 7.7% (6.4 to 9.1) 9.8% (8.3 to 11.4) 19.4% (17.4 to 21.5)
  With history of CVD 2.5% (1.7 to 3.4) 4.6% (3.6 to 5.8) 15.5% (13.6 to 17.5)
Cholesterol-lowering medication
Atorvastatin 40 mg, once daily
  Without history of CVD 59.1% (56.6 to 61.5) 62.7% (60.2 to 65.2) 76.8% (74.5 to 78.9)
  With history of CVD 13.7% (12.0 to 15.5) 26.5% (24.3 to 28.9) 52.5% (49.9 to 55.1)
Antiplatelet medication
Aspirin 100 mg, once daily
  Without history of CVD 52.1% (49.6 to 54.5) 49.1% (46.5 to 51.7) 60.3% (57.7 to 62.8)
  With history of CVD 4.3% (3.4 to 5.5) 7.2% (5.9 to 8.6) 23.9% (21.7 to 26.2)
  1. Acronyms: CI Confidence interval; CVD Cardiovascular disease; GP General practitioner