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Table 3 Univariate and Multivariate analyses by Cox-proportional hazards model

From: High percent body fat mass predicts lower risk of cardiac events in patients with heart failure: an explanation of the obesity paradox

Parameters

Univariate model

Multivariate model

model 1

model 2

model 3

HR

95% CI

p value

HR

95% CI

p value

HR

95% CI

p value

HR

95% CI

p value

Age, yrs

1.003

(0.978–1.029)

0.808

1.001

(0.976–1.028)

0.912

0.990

(0.963–1.017)

0.460

0.993

(0.966–1.021)

0.616

Sex, male

0.848

(0.424–1.697)

0.641

0.852

(0.422–1.717)

0.653

0.650

(0.320–1.320)

0.233

0.787

(0.374–1.655)

0.528

Increased FM, yes

0.457

(0.225–0.925)

0.030

0.450

(0.221–0.916)

0.028

0.458

(0.223–0.938)

0.033

0.582

(0.275–1.233)

0.158

Muscle wasting, yes

0.967

(0.458–2.043)

0.930

0.880

(0.413–1.877)

0.741

0.868

(0.391–1.925)

0.728

0.837

(0.369–1.896)

0.669

eGFR, ml/min/1.73 m2

0.978

(0.964–0.993)

0.004

   

0.978

(0.962–0.993)

0.005

0.986

(0.969–1.004)

0.122

Diabetes, yes

1.560

(0.779–3.126)

0.210

   

1.190

(0.563–2.517)

0.649

1.108

(0.511–2.401)

0.794

NT-proBNP, pg/ml

1.884

(1.391–2.552)

< 0.001

      

1.488

(1.030–2.150)

0.034

  1. eGFR estimated glomerular filtration ratio, HR hazard ratio, CI confidence interval
  2. Increased percent body fat mass (increased FM) was defined as percent body fat > 25% in males and > 30% in females
  3. Muscle wasting, i.e., reduction in skeletal muscle mass, was defined as appendicular skeletal muscle mass index < 7.0 kg/m2 in males and < 5.4 kg/m2 in females