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Table 4 Model 1: Results of linear mixed model for effect of dementia (CDR-SoB) measured at baseline on P-ADL level over time

From: Course of activities of daily living in nursing home residents with dementia from admission to 36-month follow-up

Covariates

Unadjusted models

Adjusted models

Regr. coeff. (SE)

p-value1

Regr. coeff. (SE)

p-value1

Effect of main variable

 Time

0.19 (0.12)

0.109

0.19 (0.12)

0.102

 Time*Time

0.01 (0.01)

0.198

0.01 (0.01)

0.207

 Time*Time*Time

−0.0003 (0.0002)

0.053

−0.0003 (0.0002)

0.054

 CDR-SoB BL

0.59 (0.05)

< 0.001

0.57 (0.06)

< 0.001

 Time*CDR-SoB BL

− 0.004 (0.01)

0.726

− 0.003 (0.01)

0.736

 Time*Time*CDR-SoB BL

−0.0006 (0.0008)

0.438

−0.0006 (0.0008)

0.440

 Time*Time*Time* CDR-SoB BL

0.00002 (0.00002)

0.176

0.00002 (0.00002)

0.175

Effect of additional variables at baseline

 Socio –demographic information

  Age (per years)

0.007 (0.02)

0.771

0.01 (0.02)

0.669

  Women

−0.53 (0.34)

0.126

− 0.14 (0.36)

0.702

  Single

−0.81 (0.36)

0.023

−0.91 (0.38)

0.016

 GMHR

  Poor / Fair (Good/Excellent– ref.)

1.89 (0.33)

< 0.001

1.68 (0.33)

< 0.001

 NPI-NH

  Agitation sub-syndrome

0.006 (0.02)

0.812

0.02 (0.03)

0.379

  Psychosis sub-syndrome

−0.02 (0.04)

0.579

− 0.03 (0.05)

0.521

  Affective sub-syndrome

−0.02 (0.03)

0.577

−0.04 (0.03)

0.231

  Apathy

0.15 (0.06)

0.020

0.14 (0.06)

0.029

 Use of psychotropic medication

  Antipsychotics

−0.38 (0.50)

0.454

−0.10 (0.51)

0.850

  Antidepressants

0.14 (0.36)

0.695

0.18 (0.37)

0.631

  Anxiolytics

−0.41 (0.45)

0.370

−0.46 (0.46)

0.324

  Hypnotics/Sedatives

0.49 (0.39)

0.210

0.50 (0.39)

0.196

  Anti-dementia medication

−0.98 (0.36)

0.007

−0.63 (0.36)

0.084

 NH Characteristics

  RU (SCU – ref.)

1.06 (0.37)

0.004

0.51 (0.39)

0.188

  1. CDR-SoB: The sum score of the domains in the Clinical Dementia Rating scale, BL: Baseline, GMHR: General Medical Health rating scale, NPI-NH: Neuropsychiatric Inventory 12-item Nursing Home version, NH: Nursing home, RU: Regular unit, SCU: Special care unit
  2. N = 515 at T1, N = 393 at T2, N = 332 at T3, N = 271 at T4, N = 233 at T5, N = 184 at T6, N = 147 at T7
  3. T1: baseline, T2: 6-month assessment, T3: 12-month assessment, T4: 18-month assessment, T5: 24-month assessment, T6: 30-month assessment, T7: 36-month assessment
  4. 1Bold text indicate p-value < 0.05