Effect of a patient-centred deprescribing procedure in older multimorbid patients in Swiss primary care - A cluster-randomised clinical trial

Table 1 Mean number of drugs in both groups

	Intervention group mean dpp (95% CI)	Control group mean dpp (95% CI)	Difference between groups mean dpp (95% CI) P-value
Pre-Intervention (T0)	8.02 (7.59–8.46)	8.05 (7.71–8.40)	−0.03 (− 0.59–0.53)	0.916
Post-Intervention (T1)	7.20 (6.81–7.60)^a	8.05 (7.71–8.40)	−0.85 (−1.38–0.32)	0.002
6 months (T2)	7.54 (7.07–8.37) ^a	8.01 (7.56–8.37)^b	− 0.47 (− 1.07–0.12)	0.118
12 months (T3)	7.64 (7.17–8.12) ^a	7.68 (7.32–8.00) ^b	−0.04 (− 0.63–0.56)	0.906

The mean number of drugs per patient (DPP) at all four-time points and between-group differences. T0 = First consultation, before intervention, T1 = First consultation, immediately after the intervention, T2 = Second consultation 6 months later, T3 = Third consultation 12 months later. CI = 95% confidence interval, ^a) p-values for the time point comparison within the intervention group: T1-T0, T2-T0 and T3-T0: < 0.001, 0.002 and 0.059. ^b) p-value for the time point comparison within the control group: T2-T0 and T3-T0: 0.960 and 0.065

ISSN: 1471-2318