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Table 2 Risk factors for the development of early post-transplant infection in younger recipients

From: Epidemiology, risk factors, and clinical impact of early post-transplant infection in older kidney transplant recipients: the Korean organ transplantation registry study

<  60 year-old Univariate Multivariate
HR (95% CI) p HR (95% CI) p
Sex, female 1.276 (1.074–1.515) 0.006 1.323 (1.103–1.587) 0.003
BMI (kg/m2) 1.017 (0.993–1.041) 0.173   
Cause of ESRD
 Diabetes mellitus 1    
 Hypertension 1.007 (0.756–1.341) 0.964   
 Glomerulonephritis 1.007 (0.796–1.275) 0.952   
 ADPKD 1.100 (0.712–1.700) 0.666   
 Others 1.209 (0.761–1.921) 0.421   
 Unknown 0.913 (0.691–1.205) 0.518   
Duration of dialysis (month) 1.002 (1.001–1.003) <  0.001 1.000 (0.999–1.002) 0.377
Diabetes mellitus 1.015 (0.834–1.237) 0.879   
Hypertension 1.021 (0.779–1.336) 0.882   
Cardiovascular disease 1.520 (1.167–1.980) 0.002 1.454 (1.108–1.906) 0.007
Creatinine, baseline (mg/dL) 1.004 (0.979–1.030) 0.761   
Creatinine, discharge (mg/dL) 1.015 (0.916–1.125) 0.772   
Re-transplantation 1.065 (0.782–1.450) 0.690   
Deceased donor 1.553 (1.306–1.846) <  0.001 1.409 (1.120–1.772) 0.003
Donor age (year) 1.010 (1.003–1.017) 0.004 1.008 (1.001–1.015) 0.022
Donor sex, female 1.346 (1.129–1.604) 0.001 1.192 (0.992–1.433) 0.061
Desensitization 1.015 (0.829–1.243) 0.883   
ABO incompatibility 0.757 (0.586–0.979) 0.034 0.934 (0.708–1.230) 0.626
Presence of DSA 1.536 (1.128–2.092) 0.006 1.427 (1.016–2.006) 0.040
Length of hospitalization after KT (day) 1.015 (1.011–1.020) <  0.001 1.011 (1.006–1.017) <  0.001
Induction immunosuppression
No use 1   1  
 Basiliximab 2.226 (0.831–5.959) 0.111 2.511 (0.479–8.252) 0.051
 ATG 2.760 (1.016–7.493) 0.046 2.589 (0.952–7.042) 0.062
 Basiliximab + ATG 2.894 (0.953–8.793) 0.061 2.337 (0.767–7.118) 0.135
Calcineurin inhibitors
 No use 1    
 Tacrolimus 1.345 (0.503–3.597) 0.555   
 Cyclosporine 1.146 (0.377–3.481) 0.810   
Steroid 1.477 (0.735–2.970) 0.273   
Acute rejection 2.993 (2.499–3.585) <  0.001 2.637 (2.455–3.426) <  0.001
  1. BMI body mass index, ESRD end stage renal disease, ADPKD autosomal dominant polycystic kidney disease, DSA donor specific antibody, KT kidney transplantation, ATG anti-thymocyte globulin