|
< 60 year-old
|
Univariate
|
Multivariate
|
|---|
|
HR (95% CI)
|
p
|
HR (95% CI)
|
p
|
|---|
|
Sex, female
|
1.276 (1.074–1.515)
|
0.006
|
1.323 (1.103–1.587)
|
0.003
|
|
BMI (kg/m2)
|
1.017 (0.993–1.041)
|
0.173
| | |
|
Cause of ESRD
|
|
Diabetes mellitus
|
1
| | | |
|
Hypertension
|
1.007 (0.756–1.341)
|
0.964
| | |
|
Glomerulonephritis
|
1.007 (0.796–1.275)
|
0.952
| | |
|
ADPKD
|
1.100 (0.712–1.700)
|
0.666
| | |
|
Others
|
1.209 (0.761–1.921)
|
0.421
| | |
|
Unknown
|
0.913 (0.691–1.205)
|
0.518
| | |
|
Duration of dialysis (month)
|
1.002 (1.001–1.003)
|
< 0.001
|
1.000 (0.999–1.002)
|
0.377
|
|
Diabetes mellitus
|
1.015 (0.834–1.237)
|
0.879
| | |
|
Hypertension
|
1.021 (0.779–1.336)
|
0.882
| | |
|
Cardiovascular disease
|
1.520 (1.167–1.980)
|
0.002
|
1.454 (1.108–1.906)
|
0.007
|
|
Creatinine, baseline (mg/dL)
|
1.004 (0.979–1.030)
|
0.761
| | |
|
Creatinine, discharge (mg/dL)
|
1.015 (0.916–1.125)
|
0.772
| | |
|
Re-transplantation
|
1.065 (0.782–1.450)
|
0.690
| | |
|
Deceased donor
|
1.553 (1.306–1.846)
|
< 0.001
|
1.409 (1.120–1.772)
|
0.003
|
|
Donor age (year)
|
1.010 (1.003–1.017)
|
0.004
|
1.008 (1.001–1.015)
|
0.022
|
|
Donor sex, female
|
1.346 (1.129–1.604)
|
0.001
|
1.192 (0.992–1.433)
|
0.061
|
|
Desensitization
|
1.015 (0.829–1.243)
|
0.883
| | |
|
ABO incompatibility
|
0.757 (0.586–0.979)
|
0.034
|
0.934 (0.708–1.230)
|
0.626
|
|
Presence of DSA
|
1.536 (1.128–2.092)
|
0.006
|
1.427 (1.016–2.006)
|
0.040
|
|
Length of hospitalization after KT (day)
|
1.015 (1.011–1.020)
|
< 0.001
|
1.011 (1.006–1.017)
|
< 0.001
|
|
Induction immunosuppression
|
|
No use
|
1
| |
1
| |
|
Basiliximab
|
2.226 (0.831–5.959)
|
0.111
|
2.511 (0.479–8.252)
|
0.051
|
|
ATG
|
2.760 (1.016–7.493)
|
0.046
|
2.589 (0.952–7.042)
|
0.062
|
|
Basiliximab + ATG
|
2.894 (0.953–8.793)
|
0.061
|
2.337 (0.767–7.118)
|
0.135
|
|
Calcineurin inhibitors
|
|
No use
|
1
| | | |
|
Tacrolimus
|
1.345 (0.503–3.597)
|
0.555
| | |
|
Cyclosporine
|
1.146 (0.377–3.481)
|
0.810
| | |
|
Steroid
|
1.477 (0.735–2.970)
|
0.273
| | |
|
Acute rejection
|
2.993 (2.499–3.585)
|
< 0.001
|
2.637 (2.455–3.426)
|
< 0.001
|
- BMI body mass index, ESRD end stage renal disease, ADPKD autosomal dominant polycystic kidney disease, DSA donor specific antibody, KT kidney transplantation, ATG anti-thymocyte globulin
