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Table 2 Health-related quality of life of patients with versus without prolonged CNSD use

From: Health-related quality of life in hospitalized older patients with versus without prolonged use of opioid analgesics, benzodiazepines, and z-hypnotics: a cross-sectional study

 

Prolonged CNSD use

 

No (n = 146)

Yes (n = 100)

p-value

Dimensions of HRQoL, n (%)

Mobility

   

 No problems in walking about

60 (42)

16 (17)

< 0.001

 Some problems in walking about

59 (41)

52 (54)

 Being confined to bed

24 (17)

28 (29)

Self-care

 No problems with self-care

109 (76)

50 (52)

< 0.001

 Some problems with self-care

28 (20)

40 (42)

 Being unable to wash or dress myself

6 (4)

6 (6)

Usual activities

 No problems with performing my usual activities

77 (54)

16 (17)

< 0.001

 Some problems with performing my usual activities

45 (31)

61 (63)

 Being unable to perform my usual activities

21 (15)

19 (20)

Pain/discomfort

 No pain or discomfort

48 (34)

19 (20)

0.02

 Moderate pain or discomfort

76 (53)

53 (55)

 Extreme pain or discomfort

19 (13)

24 (25)

Anxiety/depression

 Not being anxious or depressed

96 (67)

40 (42)

< 0.001

 Being moderately anxious or depressed

44 (31)

47 (49)

 Being extremely anxious or depressed

3 (2)

9 (9)

 EQ VAS, mean (SD)

62 (23)

50 (17)

< 0.001

 Global score of HRQoL (EQ-5D index), median (IQR)

0.73 (0.30 to 0.81)

0.19 (0.002 to 0.69)

< 0.001

  1. Abbreviations: CNSDs Central nervous system depressant drugs; VAS Visual analogue scale, SD Standard deviation, IQR Interquartile range