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Table 3 The laboratory findings, complications, treatment and clinical outcome in the older patients

From: Clinical characteristics and manifestations in older patients with COVID-19

  Younger old (n = 216) Oldest-old (n = 91) P
Age (years) 66.0 (63.0–69.0) 79.0 (76.0–82.0) < 0.001
Male 96 (44.4%) 57 (62.6%) 0.004
Comorbidity
 Any 143 (66.2%) 79 (86.8%) < 0.001
 Hypertension 96 (44.4%) 62 (68.1%) < 0.001
 Diabetes 37 (17.1%) 15 (16.5%) 0.890
 CAD 27 (12.5%) 23 (25.3%) 0.006
 Cerebral infarction 8 (3.7%) 13 (14.3%) 0.001
 Cancer 6 (2.8%) 3 (3.3%) 1.000
 CKD 3 (1.4%) 4 (4.4%) 0.233
 COPD 3 (1.4%) 4 (4.4%) 0.233
Laboratory findings
 White blood cells (109/L) 5.72 (4.34–7.39) 5.96 (4.74–8.12) 0.155
 Neutrophils (109/L) 3.70 (2.54–5.47) 4.30 (3.37–6.54) 0.006
 Lymphocytes (109/L) 1.18 (0.73–1.68) 0.85 (0.59–1.29) < 0.001
  < 0.8 58 (26.9%) 43 (47.3%) 0.001
 Hemoglobin (g/L) 121.0 (112.0–131.0) 121.0 (109.0–133.0) 0.660
 Platelet (109/L) 213.0 (165.3–269.5) 197.0 (134.0–242.0) 0.011
  < 100 10 (4.6%) 9 (9.9%) 0.081
 CRP (mg/L) 18.90 (1.37–73.09) 53.55 (12.28–73.03) 0.001
 ALT (U/L) 24.0 (16.0–35.8) 23.0 (16.0–39.0) 0.829
 AST (U/L) 25.0 (18.0–35.8) 30.0 (21.0–48.0) 0.002
 Albumin (g/L) 37.1 (33.6–40.0) 35.0 (32.0–37.7) < 0.001
  < 30 11 (5.1%) 7 (7.7%) 0.376
 Urea nitrogen (mmol/L) 5.10 (4.00–6.51) 7.70 (4.80–11.31) < 0.001
 Creatinine (μmol/L) 60.0 (50.0–70.0) 68.0 (57.0–100.0) < 0.001
 Blood glucose (mmol/L) 5.80 (5.06–7.74) 5.79 (4.90–7.01) 0.658
 Creatine kinase (U/L) 59.0 (42.0–86.5) 62.0 (42.5–150.0) 0.103
 LDH (U/L) 252.0 (200.0–346.0) 289.0 (230.0–452.0) 0.001
 CK-MB (ng/mL) 1.12 (0.83–1.63) 2.27 (1.32–4.43) < 0.001
 cTnI (ng/mL) 0.006 (0.006–0.014) 0.027 (0.010–0.193) < 0.001
Complications
 ARDS 56 (25.9%) 32 (35.2%) 0.102
 Acute cardiac injury 23/215 (10.7%) 43/91 (47.3%) < 0.001
  With history of cardiovascular disease 19/108 (17.6%) 37/70 (52.9%) < 0.001
  Without history of cardiovascular disease 4/107 (3.7%) 6/21 (28.6%) 0.001
 Heart failure (elevated BNP) 21/185 (11.4%) 18/84 (21.4%) 0.030
 New or worsening arrhythmia 54 (25.0%) 17 (18.7%) 0.230
 Acute liver injury 20 (9.3%) 15 (16.5%) 0.069
 Acute kidney injury 4 (1.9%) 9 (9.9%) 0.004
 Skeletal muscle injury 9/204 (4.4%) 11/81 (13.6%) 0.006
Clinical outcome
 Discharge 191 (88.4%) 59 (64.8%) < 0.001
 Death 25 (11.6%) 32 (35.2%)