Table 1 Demographic data for each group at baseline
Observation | Control | Intervention | ||
|---|---|---|---|---|
N | 94 | 36 | 37 | |
Symptom onset to randomisation (days) | 25.7 (20.1) | 22.6 (20.9) | 17.8 (19.7) | |
Age (years) | 72.1 (10.9) | 74.9 (9.2) | 75.0 (12.0) | |
Sex (male) | 59 (62.8%) | 23 (63.9%) | 27 (73.0%) | |
Ethnicity (White British) | 94 (100.0%) | 36 (100.0%) | 37 (100.0%) | |
Smoking status | Non-smoker | 38 (40.4%) | 17 (47.2%) | 26 (70.3%) |
Ex-smoker | 29 (30.9%) | 14 (38.9%) | 10 (27.0%) | |
Current smoker | 6 (6.4%) | 5 (13.9%) | 1 (2.7%) | |
Alcohol (units/wk) | 0.0 (0.0, 15.8) | 3.0 (0.0, 20.0) | 2.0 (0.0, 9.0) | |
Diagnosis | TIA | 40 (42.6%) | 11 (30.6%) | 10 (27.0%) |
Stroke | 54 (57.4%) | 25 (69.4%) | 27 (73.0%) | |
OCSP classification | LACS | 27 (50.0%) | 9 (36.0%) | 11 (40.7%) |
PACS | 13 (24.1%) | 13 (52.0%) | 11 (40.7%) | |
TACS | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | |
POCS | 14 (25.9%) | 3 (12.0%) | 5 (18.5) | |
Past medical history | AF | 25 (26.6%) | 6 (16.7%) | 10 (27.0%) |
Diabetes | 19 (20.2%) | 7 (19.4%) | 5 (13.5%) | |
IHD | 11 (11.7%) | 4 (11.1%) | 6 (16.2%) | |
Stroke | 44 (46.8%) | 12 (33.3%) | 21 (56.8%) | |
TIA | 36 (38.3%) | 6 (16.7%) | 7 (18.9%) | |
Hypertension | 53 (56.4%) | 20 (55.6%) | 25 (67.6%) | |
Rockwood Frailty Score | 4.0 (3.0, 6.0) | 5.0 (4.0, 6.0) | 6.0 (4.5, 6.0) | |
MoCA | 27.4 (1.4) | 23.4 (1.4) | 23.2 (1.5) | |
Clinic BP (mmHg) | Systolic | 147.3 (20.5) | 148.1 (21.0) | 145.2 (19.5) |
Diastolic | 79.6 (10.5) | 78.9 (11.5) | 81.8 (12.5) | |
Total Cholesterol (mmol/L) | 4.9 (1.2) | 4.9 (1.2) | 4.6 (1.4) | |
Heart rate (beats per min)a | 76.6 (18.9) | 75.9 (16.8) | 80.4 (10.2) | |
On anticoagulationa | 10/25 (40.0%) | 3/6 (50.0%) | 3/10 (30.0%) | |
HbA1C (mmol/mol)b | 52.5 (47.3, 69.5) | 49.5 (43.0, 82.3) | 73.0 (51.8, 106.3) |