Fig. 1

a, b, c. This figure shows an example of normal (a) and two amyloid pathological PET results (b, c). After considering only subjects with pathological PET examination, it emerges from the mean of the uptake values of 18F-Flutemetamol a widespread and pathological deposition of cerebral amyloid. In the first patient (b) a lower involvement of sensory-motor regions of the right and left (average values of z-score of 3.25 ± 2.44 and 3.01 ± 2.42, respectively), occipital left and right (average values of z-score of 3.83 ± 3.75 and 3.15 ± 3.08, respectively) and right and left medial temporal region which remains the cortical area less involved by amyloid pathology (mean values of z-score of 0.83 ± 1.59 and 0.47 ± 1.60, respectively). In the second patient (c), the amyloid deposition is more abundant probably expression of advanced disease. There is a higher involvement of sensory-motor regions of the right and left (average values of z-score of 9.52 ± 1.01 and 9.45 ± 1.02, respectively), and occipital regions of the right and left (average values of z-score of 13.11 ± 1.10 and 12.30 ± 1.06, respectively) and right and left medial temporal region which remain the cortical area less involved by amyloid pathology (mean values of z-score of 3.56 ± 0.65 and 2.82 ± 0.62, respectively)