Table 1 The drug groups commonly involved in drug-related problems in the total cohort (2465 patients at 41 nursing homes)
From: Variation between nursing homes in drug use and in drug-related problems
Drug-related problems (DRPs) | Drugs | The drug groups commonly involved in the drug-related problems listed | |||||
|---|---|---|---|---|---|---|---|
Categories of DRPs | n (%) | ATC-N drugsa n (%) | All other drugs n (%) | No. 1 | n of drugs | No. 2 | n of drugs |
Need for additional drug (1a) | 372 (7.7) | 50 (13.4) | 322 (86.6) | B vitaminsb | 155 | Iron supplements | 39 |
Unnecessary drug (1b) | 1544 (31.9) | 474 (30.7) | 1070 (69.3) | Benzodiazepinesc | 185 | Antidepressants | 121 |
Inappropriate drug choice (1c) | 382 (7.9) | 131 (34.3) | 251 (65.7) | Benzodiazepines | 60 | Opioidsd | 31 |
Excess dosing (2a) | 688 (14.2) | 291 (42.3) | 397 (57.7) | Benzodiazepines | 110 | Proton pump inhibitors | 103 |
Under-dosing (2b) | 160 (3.3) | 71 (44.4) | 89 (55.6) | Opioids | 23 | Thyroid therapy | 23 |
Adverse drug reaction (3) | 276 (5.7) | 134 (48.6) | 142 (51.4) | Benzodiazepines | 63 | Antipsychotics | 28 |
Drug–drug interactionse (4) | 419 (8.6) | 207 (49.4) | 212 (50.6) | Antidepressants | 115 | Antithrombotic agentsf | 55 |
Monitoring of drug use required (6a) | 687 (14.2) | 329 (47.9) | 358 (52.1) | Antidepressants | 105 | Antipsychotics | 50 |
Otherg | 364 (6.5) | 88 (24.2) | 276 (75.8) | Beta-blockers | 33 | Paracetamol | 25 |
DRPs (total) | 4847 (100) | 1775 (36.6%) | 3072 (63.4%) | Benzodiazepines | 489 | Antidepressants | 456 |