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Table 3 Underlying and Direct Causes of Death among Men and Women

From: Causes of death in a nationwide cohort of community-dwellers with Alzheimer’s disease

Category

Men N = 10,934

Women N = 19,707

P for sex difference

No AD n = 3654

AD n = 7280

No AD n = 6517

AD n = 13,190

Diseases of the circulatory system

1842 (50.4)

2202 (30.2)

3599 (55.2)

4282 (32.5)

0.078

Diseases of the nervous system

123 (3.4)

3541 (48.6)

317 (4.9)

6677 (50.6)

0.006

Neoplasms

830 (22.7)

667 (9.2)

1112 (17.1)

906 (6.9)

0.56

Mental and behavioral disorders

191 (5.2)

152 (2.1)

550 (8.4)

273 (2.1)

< 0.001

Diseases of the respiratory system

280 (7.7)

228 (3.1)

232 (3.6)

152 (1.2)

0.13

External causes of morbidity and mortality

141 (3.9)

197 (2.7)

215 (3.3)

321 (2.4)

0.71

Diseases of the digestive system

101 (2.8)

136 (1.9)

207 (3.2)

287 (2.2)

0.94

Certain infectious and parasitic diseases

30 (0.8)

37 (0.5)

59 (0.9)

59 (0.4)

0.46

Diseases of the genitourinary system

46 (1.3)

45 (0.6)

86 (1.3)

111 (0.8)

0.31

Endocrine, nutritional and metabolic diseases

41 (1.1)

44 (0.6)

74 (1.1)

72 (0.5)

0.67

Diseases of the musculoskeletal system and connective tissue

12 (0.3)

4 (0.1)

37 (0.6)

17 (0.1)

0.64

Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

3 (0.1)

5 (0.1)

7 (0.1)

6 (< 0.1)

0.46

Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified

6 (0.2)

7 (0.1)

4 (0.1)

10 (0.1)

0.36

Congenital malformations, deformations and chromosomal abnormalities

1 (< 0.1)

5 (0.1)

7 (0.1)

8 (0.1)

0.22

Diseases of the skin and subcutaneous tissue

4 (0.1)

2 (< 0.1)

5 (0.1)

2 (< 0.1)

0.84

Diseases of the eye, adnexa, ear and mastoid process

1 (< 0.1)

0 (0.0)

1 (< 0.1)

0 (0.0)

N.A