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Table 3 Agreement (kappa statistic and standard error) between self-reported morbidity in TILDA and Rx-Risk-V algorithm (≥ 65 years)

From: Agreement between self-reported morbidity and pharmacy claims data for prescribed medications in an older community based population

TILDA Rx-Risk-V Pharmacy claims Kappa
(κ)
Standard Error
Self-reported morbidity N % Medication-based Morbidity (ATC) N %
Diabetes or high blood sugar 222 (12.13) Diabetes (A10AB01-A10BG03, A10BH, A10BX) 191 (10.44) 0.81 0.02
Glaucoma 82 (4.48) Glaucoma (S01EA01-S01EB03, S01EC03-S01EX) 104 (5.68) 0.69 0.02
Osteoporosis 253 (13.83) Osteoporosis/Paget’s disease (M05BA01-M05BB09, M05BX03, G03XC01, A12AX92) 306 (16.72) 0.61 0.02
Parkinson 17 (0.93) Parkinson’s disease (N04AA01-N04BX02) 40 (2.19) 0.56 0.02
Angina 213 (11.64) Angina (C01DA02-C01DA14, C01DX16, C01EB17-C01EB18) 194 (10.60) 0.51 0.02
High Cholesterol 733 (40.05) Hyperlipidaemia (C10AA01-C10BX17) 1002 (54.75) 0.44 0.02
Manic depression 5 (0.27) Bipolar disorder (N05AN01) 6 (0.33) 0.36 0.02
High blood pressure or Hypertension 964 (52.68) Hypertension (C03AA01-C03BA11, C03DA01-C03EA01, C09BA02-C09BA09, C09DA01-C09DA09, C02AB01-C02AC05, C02DB02-C02KX01) 591 (32.30) 0.36 0.02
Pain (taking pain medication) 464 (25.36) Pain (Opioids) (N02AA01-N02AX02)
Pain (Inflammation) (M01AB01, M01AH06)
523 (28.58) 0.35 0.02
Pain 726 (39.67) Pain (Opioids) (N02AA01-N02AX02)
Pain (Inflammation) (M01AB01, M01AH06)
523 (28.58) 0.27 0.02
Abnormal Heart Rhythm 221 (12.08) Arrhythmia (C01AA05, C01BA01-C01BD01, C01BD07) 103 (5.63) 0.26 0.02
Depression 78 (4.26) Depression (N06AA01-N06AG02, N06AX) 359 (19.62) 0.21 0.02
Dementia 5 (0.27) Dementia (N06DA02, N06DA01) 24 (1.31) 0.20 0.02
Chronic lung disease such as chronic bronchitis or emphysema 97 (5.30) Chronic airways disease (R03AC02-R03DC03) 457 (24.97) 0.19 0.02
Cancer or a malignant tumour 177 (9.67) Malignancies (L01AA01-L01XX31) 62 (3.39) 0.19 0.02
Emotional nervous or psychiatric problem, such as depression or anxiety 115 (6.28) Anxiety (N05BA01- N05BA12) 327 (17.87) 0.15 0.02
Congestive heart failure 31 (1.69) Chronic heart failure (C03CA01-C03CC01, C09AA01-C09AA10, C09CA01, C09CA03, C09CA06-C09CA07) 269 (14.70) 0.13 0.01
Cirrhosis or serious liver damage 10 (0.55) Liver disease (A05AA01-A05BA08, J05AF05, J05AF07, J05AF11) 6 (0.33) 0.12 0.02
Heart attack (including myocardial infarction or coronary thrombosis) 171 (9.34) Anti-platelet therapy (B01AC04-B01AC30) 952 (52.02) 0.11 0.01
Anxiety 66 (3.61) Anxiety (N05BA01-N05BA12) 327 (17.87) 0.11 0.02
Stomach ulcers 127 (6.94) GORD & Peptic ulcer (A02BA, A02BC) 947 (51.75) 0.10 0.01
Alcohol or substance abuse 28 (1.53) Alcohol dependence (N07BB01, N07BB04) 1 (0.05) 0.07 0.01
Any other heart trouble 101 (5.52) Ischaemic heart disease/hypertension (C07AA01-C07FB07, C08CA01-C08DB01) 884 (48.31) 0.06 0.01
Stroke (cerebral vascular disease) 61 (3.33) Anti-platelet therapy (B01AC04-B01AC30) 952 (52.02) 0.04 0.01
Mini-stroke or TIA 131 (7.16) Anti-platelet, Anti-coagulation therapya (B01AC04-B01AC30, B01AA03-B01AB06, B01AB10) 1104 (60.32) 0.02 0.01
Incontinence 313 (17.10) Neurogenic Bladder & Urinary Incontinence (V07AN) 17 (0.93) 0.02 0.01
Psychosis 1 (0.05) Psychotic illness (N05AA01- N05AX17) 150 (8.20) 0.01 0.00
  1. ATC Anatomical Therapeutic Chemical
  2. GORD Gastro-Oesophageal Reflux Disease
  3. aAnti-coagulant counted if patient prescribed antiarrhythmic for Atrial Fibrillation (i.e., if patient not in sinus rhythm) [33]