Table 1 Demographic data of patients with and without dementia before and after propensity score matching
Before matching | After matching | |||||
|---|---|---|---|---|---|---|
Non-Dementia (N = 287,515) | Dementia (N = 28,865) | p-value | Non-Dementia (N = 57,712) | Dementia (N = 28,864) | p-value | |
Age, median (IQR) | 76 (73 ~ 80) | 79 (75 ~ 93) | 79 (75–83) | 79 (75–83) | ||
70–80 years | 214,874 (74.7) | 15,894 (55.1) | < 0.001 | 31,621 (54.8) | 15,894 (55.1) | 0.400 |
80–90 years | 65,342 (22.7) | 11,041 (38.2) | 22,098 (38.3) | 11,041 (38.3) | ||
≥ 90 years | 7,299 (2.6) | 1,930 (6.7) | 3,993 (6.9) | 1,929 (6.7) | ||
Sex, female | 170,007 (59.1) | 20,005 (69.3) | < 0.001 | 40,338 (69.9) | 20,004 (69.3) | 0.744 |
Co-morbid disease | ||||||
Hypertension | 203,036 (70.6) | 22,848 (79.2) | < 0.001 | 46,059 (79.8) | 22,848 (79.2) | 0.371 |
Dyslipidemia | 157,248 (54.7) | 17,545 (60.8) | < 0.001 | 35,262 (61.1) | 17,545 (60.8) | 0.761 |
Ischemic heart disease | 81,060 (28.2) | 10,123 (35.1) | < 0.001 | 20,201 (35.0) | 10,123 (35.1) | 0.843 |
Heart failure | 41,404 (14.4) | 6,266 (21.7) | < 0.001 | 12,353 (21.4) | 6,266 (21.7) | 0.305 |
Atrial fibrillation | 10,614 (3.7) | 1,491 (5.2) | < 0.001 | 2,603 (4.5) | 1,491 (5.2) | < 0.001 |
Diabetes Mellitus | 113,939 (39.6) | 14,113 (48.9) | < 0.001 | 28,084 (48.7) | 14,113 (48.9) | 0.519 |
Cerebrovascular disease | 76,776 (26.7) | 12,863 (44.6) | < 0.001 | 25,917 (44.9) | 12,863 (44.6) | 0.338 |
Depression | 52,179 (18.2) | 8,555 (29.6) | < 0.001 | 16,923 (29.3) | 8,555 (29.6) | 0.336 |
Bipolar disorder | 2,853 (1.0) | 540 (1.9) | < 0.001 | 889 (1.5) | 540 (1.9) | 0.003 |
Schizophrenia | 1,662 (0.6) | 354 (1.2) | < 0.001 | 460 (0.8) | 354 (1.2) | < 0.001 |
Anxiety | 97,503 (33.9) | 13,385 (46.4) | < 0.001 | 26,680 (46.2) | 13,385 (46.4) | 0.691 |
Insomnia | 78,382 (27.3) | 11,320 (39.2) | < 0.001 | 22,611 (39.2) | 11,320 (39.2) | 0.911 |
Substance abuse | 1,663 (0.6) | 307 (1.1) | < 0.001 | 498 (0.9) | 307 (1.1) | 0.004 |
Tobacco dependence and Tobacco use | 113 (0.0) | 15 (0.02) | 0.308 | 22 (0.04) | 15 (0.02) | 0.353 |
Parkinson’s disease | 4,893 (1.7) | 1,371 (4.8) | < 0.001 | 2,305 (4.0) | 1,371 (4.8) | < 0.001 |
Obesity | 472 (0.2) | 42 (0.2) | 0.453 | 97 (0.2) | 42 (0.2) | 0.434 |
Alcohol disease | 1,566 (0.5) | 280 (1.0) | < 0.001 | 467 (0.8) | 280 (1.0) | 0.016 |