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Table 3 Multivariate RDA to identify the most important explanatory variables for microbiome composition changes

From: Dysbiosis, gut barrier dysfunction and inflammation in dementia: a pilot study

Variable

Control versus Dementia

Severity of dementia

BMI

Variance = 33.18

Variance = 33.18

F = 1.29

F = 1.29

P = 0.006

P = 0.008

Total protein

Variance = 29.19

Variance = 29.19

F = 1.14

F = 1.14

P = 0.067

P = 0.070

soluble CD14

Variance = 29.06

Variance = 29.06

F = 1.13

F = 1.13

P = 0.072

P = 0.079

Statins

Variance = 32.06

Variance = 32.06

F = 1.25

F = 1.25

P = 0.009

P = 0.014

Clock-drawing test

Variance = 25.89

Variance = 25.89

F = 1.01

F = 1.01

P = 0.376

P = 0.374

Age

Variance = 25.88

Variance = 25.88

F = 1.01

F = 1.01

P = 0.427

P = 0.409

Sex

Variance = 27.63

Variance = 27.63

F = 1.08

F = 1.08

P = 0.137

P = 0.154

NSAIDS

Variance = 28.17

Variance = 28.17

F = 1.10

F = 1.10

P = 0.098

P = 0.107

  1. BMI body mass index, NSAIDS non-steroidal anti-inflammatory drugs