Table 1 CAST Study Outcome Measures Summary

Mental functioning

Mental Component Score of VR-12 (MCS) [51, 55]

PT, CG

T₁, T₂, and T₃

-Descriptive analyses

-T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, subgroup analyses, quantile regression

-T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses, subgroup analyses

Physical functioning

Physical Component Score (PCS) of VR-12 [51, 55]

PT, CG

T₁, T₂, and T₃

-Descriptive analyses

-T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, subgroup analyses, quantile regression

-T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses, subgroup analyses

Depressive symptoms

CESD-10 [56]

PT, CG

T₁, T₂, and T₃

-Descriptive analyses

-T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, quantile regression

-T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses

Anxiety symptoms

Generalized Anxiety Disorder scale (GAD-7) [57]

PT, CG

T₁, T₂, and T₃

-Descriptive analyses

-T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, quantile regression

-T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses

Perceived social support

Personal Resource Questionnaire (PRQ-2000) [58]

PT

T₁, T₂, and T₃

-Descriptive analyses

-T1-T2 (Treatment Effect): ANCOVA, complete case and multiple imputation analyses, quantile regression

-T2-T3 (Sustainability): ANCOVA, complete case and multiple imputation analyses

Communication between patients and providers

Patient-Provider Communication questionnaire [59]

PT, CG

T₁ and T₂

-Descriptive analyses

-T1: z test of proportions for group comparison, complete case analysis

-T2: z test of proportions for group comparison, complete case analysis

Client-centredness of care

Adapted Client-Centred Care Questionnaire (CCCQ) [60]

PT, CG

T₁, T₂, and T₃

-Descriptive analyses

-T1: z test of proportions for group comparison, complete case analysis

-T2: z test of proportions for group comparison, complete case analysis

Care experience

Integrated Care Patient-Reported Experience Measures (IC-PREMs) [61]

PT, CG

T₁, and T₂

-Descriptive analyses

-T1: z test of proportions for group comparison, complete case analysis

-T2: z test of proportions for group comparison, complete case analysis

Unmet care needs

Unmet Care Needs questionnaire

PT, CG

T₁, T₂, and T₃

-Descriptive analyses

- T1: z test of proportions for group comparison, complete case analysis

-T2: z test of proportions for group comparison, complete case analysis

Caregiver strain

Modified Caregiver Strain Index (CSI) [62]

CG

T₁, T₂, and T₃

-Descriptive analyses

-T1-T2 (Treatment Effect): ANCOVA, complete case analysis

-T2-T3 (Sustainability): ANCOVA, complete case analysis

Utilization of health and social services and associated costs

Institute for Clinical Evaluative Sciences (IC/ES), Health and Social Services Utilization Inventory (HSSUI) [63, 64]

PT, CG

T₁, T₂, and T₃

-Descriptive analyses

-T1-T2 (Treatment Effect): Mann-Whitney U test, complete case analysis, Hazard Ratio (95% CI) & Risk Difference (95% CI) for 30, 90 &180-day ED visits and hospital admissions

-T2-T3 (Sustainability): Mann-Whitney U test, complete case analysis