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Table 1 Person with dementia, descriptive data by severity of cognitive impairment

From: Disease severity accounts for minimal variance of quality of life in people with dementia and their carers: analyses of cross-sectional data from the MODEM study

  Mild Moderate Severe Sig. Test
Age, mean (SD) 80.2 (7.2) 82.4 (8.8) 80.0 (9.2) F = 2.50, p = 0.08
Gender: male, N (%) 62 (56.4%) 55 (55.6%) 34 (35.1%) χ2 = 11.62, p = 0.003
Residential status: care home (v own household), N (%) 6 (5.5%) 17 (17.0%) 40 (41.2%) χ2 = 41.59, p < 0.0001
Ethnicity: White British, N (%) 105 (96.3%) 88 (89.8%) 88 (90.7%) χ2 = 13.03, p = 0.37
Diagnosis:     χ2 = 4.28, p = 0.83
AD, N (%) 63 (63.0%) 55 (57.9%) 58 (61.1%)  
VaD, N (%) 13 (13.0%) 12 (12.6%) 14 (14.7%)  
LBD, N (%) 2 (2.0%) 1 (1.1%) 3 (3.2%)  
FTD, N (%) 4 (4.0%) 4 (4.2%) 1 (1.1%)  
Other, N (%) 18 (18.0%) 23 (24.2%) 19 (20.0%)  
sMMSE (↑ better cognition), mean (SD) 24.6 (0.2) 15.1 (2.9) 3.6 (3.2) F = 1360.36, p < 0.0001
QOL SELF-REPORT
DEMQOL (↑ better QoL), mean (SD) 90.5 (13.18) 92.8 (12.6) t = −1.23, p = 0.22
CASP total (↑ better QoL), mean (SD) 40.9 (9.5) 40.1 (8.0) t = 0.58 p = 0.61
EQ-5D Index (↑ better QoL), mean (SD) 0.8 (0.2) 0.8 (0.2) t = −0.08, p = 0.94
QOL PROXY-REPORT
DEMQOL-Proxy (↑ better QoL), mean (SD) 93.5 (13.7) 94.3 (14.4) 98.1 (13.0) F = 3.18, p = 0.04
EQ-5D-proxy Index (↑ better QoL), mean (SD) 0.7 (0.3) 0.5 (0.3) 0.4 (0.3) F = 26.76, p < 0.0001
COMORBIDITIES
NPI total (↑ more neuropsychiatric symptoms), mean (SD) 12.7 (11.0) 20.1 (15.5) 24.1 (16.3) F = 15.51, p < 0.0001
  1. AD Alzheimer’s Disease, BADL Bristol Activities of Daily Living, CCI Charlson Comorbidity Index, FTD Frontotemporal Dementia, LBD Lewy Body Dementia, NPI Neuropsychiatric Inventory, QoL Quality of Life, sMMSE standardised Mini-Mental State Examination, OARS Older Adult Social Resource Scale, VaD Vascular Dementia
  2. F = F statistic derived from one-way Analysis of Variance, t = t value derived from t-test, χ2 = Chi-square value derived from a Pearson’s Chi-square test