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Table 1 Summary of the assessments in the CAIDE study

From: Third follow-up of the Cardiovascular Risk Factors, Aging and Dementia (CAIDE) cohort investigating determinants of cognitive, physical, and psychosocial wellbeing among the oldest old: the CAIDE85+ study protocol

Data collected and test/scale

Midlife-baseline examination (1972–1992)

1st late-life re-examination (1998)

2nd late-life re-examination (2005–2009)

3rd re-examination CAIDE85+ (2019–2021)

Socio-demographicsa (e.g. age; sex; self-reported education, marital status, occupation and income)

X

X

X

X

Lifestylea (questions about e.g. diet, physical exercise, smoking, leisure activities)

X

X

X

X

Anthropometric measurements (weight, height, BMI, waist circumference, blood pressure)

X

X

X

X

Blood markersa (e.g. lipids, glucose, CRP, creatinine)

X

X

X

X

Medical history (self-reported)

X

X

X

X

Medical history (national registers)

X

X

X

X

Cognition

 CERAD [30]

–

–

X

X

 MMSE [31]

–

X

Part of CERAD

Part of CERAD

 Immediate word recall (3 word-lists)b [32]

–

X

1 list

–

 Category fluency test [33]

–

X

Part of CERAD

Part of CERAD

 Purdue Peg board [34]

–

X

X

–

 Trail Making Test - part A [35]

–

–

X

X

 Stroop [36]

–

X

X

–

 Letter Digit Substitution Test [37]

–

X

X

X

 Diagnosis of dementia or MCI (3-step protocol [29])

–

X

X

–

 Diagnosis of dementia or MCI (national registers)

–

X

X

X

 Daily life functioning (questions)

X

X

X

X

 Daily life functioning (ADL: Katz Index and Lawton and Brody Scale [38,39,40])

–

–

–

X

 Daily life functioning (CDR [41, 42])

–

–

X

X

 Physical Functioning (SPPB [43])

–

–

–

X

 Stressa (questions)

X

X

X

X

 Anxiety (6-item STAI [44])

–

X

X

X

 Personality-related factors (anger expression [45], cynical distrust [46], sense of coherence [47], ways of coping [48])

–

X

–

–

 Social Network (questions)

–

X

X

Shortened

 Subjective memorya (questions)

–

X

X

X

 Hopelessness (questions)

X

X

X

X

 Depression (BDI [49])

–

X

X

X

 Significant life events (questions)

–

X

X

Shortened

 Health Related Quality of Life (RAND 36 [50])

–

–

–

X

 Frailty (Fried phenotype [51])

–

–

–

X

 Malnutrition (MNA short version [52])

–

–

–

X

 Sleep quality (Pittsburgh Sleep Index [53])

–

–

–

X

 Oral health (questions)

–

–

–

X

 Medication use (self-reported and national registers)

–

X

X

X

 APOEƐ4 genotyping

–

X

X

–

  1. ADL Activity of daily living, APOEƐ4 Apolipoprotein E Ɛ4 allele, BDI Beck depression inventory, BMI body mass index, CDR clinical dementia rating, CERAD Consortium to Establish a Registry for Alzheimer’s Disease test battery, CRP C-reactive protein, MCI Mild cognitive impairment, MMSE Mini-Mental State Examination, MNA mini nutritional assessment, SPPB Short physical performance battery, RAND36 RAND 36-Item Health Survey 1.0, STAI State trait anxiety inventory
  2. a some differences in assessments may exist among different re-examinations
  3. b of the 3 word-lists used in 1998, only one was repeated in 2005–2008
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BMC Geriatrics

ISSN: 1471-2318

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