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Table 3 Patients (n = 715) with PIMs identified with the NORGEP-NH list before and after hospitalisation

From: The impact of hospitalisation to geriatric wards on the use of medications and potentially inappropriate medications - a health register study

 Patients with PIMs
BeforeAfterRemovedNot changedAdded
n%n%n%n%n%
Part A: Single substance criteria
 1.Combination analgesic codein/paracetamol9413.18311.6476.6476.6365.0
 2. Tricyclic antidepressants (TCAs)253.5172.4111.5142.030.4
 3. Non-steroid anti-inflammatory drugs (NSAIDs)476.6273.8314.3162.2111.5
 4. First-generation antihistamines263.6294.181.1182.5111.5
 5. Diazepam567.8507.0273.8294.1212.9
 6. Oxazepam: Dosage > 30 mg/day101.4111.571.030.481.1
 7. Zopiclone: Dosage > 5 mg/day14420.114219.9283.911616.2263.6
 8. Nitrazepam263.6212.981.1182.530.4
 9. Flunitrazepam10.110.1
 10. Chlometiazole20.391.310.110.181.1
 11. Regular use of hypnoticsa19627.420628.8283.916823.5385.3
Total part A31644.232245.0608.425635.8669.2
Part B: Combinations to avoid
 12. Warfarin + NSAIDs20.320.2
 13. Warfarin + SSRIs/SNRIsb131.8131.850.781.150.7
 14. Warfarin+ ciprofloxacin/ofloxacin/erythromycin/clarithromycin30.420.330.420.3
 15. NSAIDs/coxibsc + ACE-inhibitors/AT2-antagonists162.2131.8111.550.781.1
 16. NSAIDs/coxibs + diuretics81.171.071.010.160.8
 17. NSAIDs/coxibs + glucocorticoids60.860.830.430.430.4
 18. NSAIDs/coxibs + SSRI/SNRIs71.040.671.040.6
 19. ACE-inhibitorsd/AT2-antagonistse + potassium or potassium-sparing diuretics192.7233.291.3101.4131.8
 20. Beta blocking agents + cardioselective calcium antagonists20.320.310.110.110.1
 21. Erythromycin/clarithromycin + statins10.120.310.120.3
 22.Bisphosponate + proton pump inhibitors182.5223.140.6142.081.1
 23. Concomitant use of 3 or more psychotropics527.3659.1182.5344.8314.3
 24. Tramadol + SSRIs20.371.010.110.160.8
 25. Metoprolol + paroxetine/fluoxetine/bupropion10.120.310.110.1
 26. Metformin + ACE-Inhibitors/AT2-antagonists + diuretics91.360.850.740.620.3
Total part B12918.013919.4496.98011.2598.3
Total PART A and B35749.936250.67310.228439.77810.9
  1. a regular use defined as dispensing of 60 DDD or more in the 120-day period
  2. b selective serotonin reuptake inhibitors/selective norepinephrine reuptake inhibitors
  3. ccyclooxygenase-2-selective inhibitors
  4. dangiotensin-converting enzyme inhibitors
  5. e angiotensin II receptor antagonists