From: Individual and joint trajectories of change in bone, lean mass and physical performance in older men
 | Low grip strength trajectory | Medium grip strength trajectory | High grip strength trajectory | Unable to complete grip | p-value | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|
Low BMD trajectory | Medium BMD trajectory | High BMD trajectory | Low BMD trajectory | Medium BMD trajectory | High BMD trajectory | Low BMD trajectory | Medium BMD trajectory | High BMD trajectory | |||
N = 558 | N = 532 | N = 159 | N = 774 | N = 1127 | N = 398 | N = 220 | N = 474 | N = 179 | N = 259 | ||
Age (years) | 72.3 ± 5.1 | 72.8 ± 5.3 | 72.6 ± 4.8 | 72.7 ± 5.3 | 73 ± 5.3 | 72.5 ± 5.5 | 72.8 ± 5.7 | 72.6 ± 5.4 | 72.4 ± 5.3 | 73.4 ± 5.6 | 0.143 |
Walking speed (m/s) | 1.19 ± 0.22 | 1.20 ± 0.21 | 1.18 ± 0.22 | 1.24 ± 0.21 | 1.23 ± 0.21 | 1.22 ± 0.20 | 1.27 ± 0.22 | 1.29 ± 0.20 | 1.30 ± 0.21 | 1.20 ± 0.36 | < 0001 |
Grip strength (kg) | 34.6 ± 5 | 34.6 ± 5.5 | 35.1 ± 5.7 | 43.4 ± 5 | 43.5 ± 5.1 | 43.7 ± 5.1 | 52.7 ± 6.1 | 52.9 ± 5.3 | 52.8 ± 5.9 | N/A | <.001 |
PASE | 140.5 ± 64.7 | 147.4 ± 68.7 | 145.1 ± 69.3 | 150.6 ± 68.2 | 152.2 ± 65.7 | 155.1 ± 67.9 | 162.8 ± 62.5 | 159.1 ± 68.0 | 166.9 ± 70.8 | 151.3 ± 68.8 | <.001 |
Total Hip BMD (g/cm2) | 0.826 ± 0.08 | 0.991 ± 0.06 | 1.175 ± 0.08 | 0.826 ± 0.07 | 0.989 ± 0.06 | 1.173 ± 0.09 | 0.834 ± 0.07 | 0.988 ± 0.06 | 1.18 ± 0.08 | 0.955 ± 0.15 | <.001 |
Excellent/good health | 470 (84.2) | 450 (84.6) | 140 (88.1) | 695 (89.8) | 1003 (89.0) | 351 (88.2) | 203 (92.3) | 448 (94.5) | 171 (95.5) | 208 (80.3) | <.001 |
One or more ADL limitationa | 120 (21.5) | 113 (21.2) | 35 (22) | 106 (13.7) | 167 (14.8) | 63 (15.8) | 23 (10.5) | 52 (11) | 22 (12.3) | 67 (25.9) | <.001 |
BMI (kg/m2) | 26.2 ± 3.8 | 27.9 ± 3.7 | 29.9 ± 3.8 | 26 ± 3.1 | 27.8 ± 3.7 | 29 ± 4.1 | 26.1 ± 3 | 27.8 ± 3.4 | 29.2 ± 3.5 | 27.4 ± 3.7 | <.001 |
One or more medical conditions** | 370 (66.3) | 361 (67.9) | 108 (67.9) | 431 (55.7) | 690 (61.2) | 242 (60.8) | 105 (47.7) | 252 (53.2) | 106 (59.2) | 160 (61.8) | <.001 |
ALM/ht2 (kg/m2) | 7.6 ± 0.9 | 7.9 ± 0.9 | 8.3 ± 1 | 7.8 ± 0.7 | 8.1 ± 0.9 | 8.4 ± 0.9 | 8.1 ± 0.8 | 8.4 ± 0.9 | 8.7 ± 0.9 | 8.0 ± 1.0 | <.001 |
Probability of identified trajectory | 0.89 ± 0.2 | 0.85 ± 0.2 | 0.85 ± 0.2 | 0.85 ± 0.2 | 0.84 ± 0.2 | 0.85 ± 0.2 | 0.86 ± 0.2 | 0.87 ± 0.2 | 0.89 ± 0.2 | N/A | N/A |
Identified Trajectory probability < =0.5 | 14 (2.5) | 20 (3.8) | 3 (1.9) | 23 (3) | 41 (3.6) | 15 (3.8) | 3 (1.4) | 15 (3.2) | 4 (2.2) | N/A | 0.59 |