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Table 2 Association between baseline physical activity and risk of dementia

From: Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort

 Model 1a All-cause dementiaModel 2b All-cause dementiaModel 3b Incident cases at the first follow-up visit excluded All-cause dementiaModel 4b Alzheimer’s dementiaModel 5b Incident AD cases at the first follow-up visit excluded Alzheimer’s dementia
n/N = 117/1550n/N = 117/1550n/N = 89/1521n/N = 79/1511n/N = 57/1489
HR (95%CI)pHR (95%CI)pHR (95%CI)pHR (95%CI)pHR (95%CI)p
Household/transportation activities
  ≤ 1.61 (Ref)1 (Ref)1 (Ref)1 (Ref)1 (Ref)
 ]1.6–2.0]0.53 [0.34–0.82]0.0050.55 [0.35–0.87]0.010.57 [0.34–0.97]0.040.49 [0.28–0.86]0.010.57 [0.29–1.10]0.10
  > 2.00.55 [0.34–0.90]0.020.62 [0.38–1.01]0.060.70 [0.40–1.24]0.220.65 [0.36–1.16]0.140.85 [0.43–1.68]0.65
Leisure and sport activities
 None1 (Ref)1 (Ref)1 (Ref)1 (Ref)1 (Ref)
 ]0–8.18]1.18 [0.79–1.78]0.421.36 [0.89–2.06]0.151.12 [0.69–1.81]0.661.46 [0.88–2.42]0.151.08 [0.60–1.97]0.80
  > 8.181.03 [0.57–1.86]0.921.33 [0.72–2.44]0.361.17 [0.59–2.32]0.651.43 [0.68–3.00]0.351.15 [0.48–2.73]0.76
  1. n/N = number of cases/total
  2. HR Hazard Ratio, CI Confidence Interval
  3. a Minimally adjusted Cox proportional hazard model: adjusted for age, center, sex, APOE, and education level
  4. b Multi-adjusted Cox proportional hazard model: adjusted for age, center, sex, APOE, education level, living alone, diabetes, depressive symptomatology, cardiovascular disease
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