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Table 2 Association between baseline physical activity and risk of dementia

From: Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort

 

Model 1a All-cause dementia

Model 2b All-cause dementia

Model 3b Incident cases at the first follow-up visit excluded All-cause dementia

Model 4b Alzheimer’s dementia

Model 5b Incident AD cases at the first follow-up visit excluded Alzheimer’s dementia

n/N = 117/1550

n/N = 117/1550

n/N = 89/1521

n/N = 79/1511

n/N = 57/1489

HR (95%CI)

p

HR (95%CI)

p

HR (95%CI)

p

HR (95%CI)

p

HR (95%CI)

p

Household/transportation activities

  ≤ 1.6

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 ]1.6–2.0]

0.53 [0.34–0.82]

0.005

0.55 [0.35–0.87]

0.01

0.57 [0.34–0.97]

0.04

0.49 [0.28–0.86]

0.01

0.57 [0.29–1.10]

0.10

  > 2.0

0.55 [0.34–0.90]

0.02

0.62 [0.38–1.01]

0.06

0.70 [0.40–1.24]

0.22

0.65 [0.36–1.16]

0.14

0.85 [0.43–1.68]

0.65

Leisure and sport activities

 None

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

1 (Ref)

 ]0–8.18]

1.18 [0.79–1.78]

0.42

1.36 [0.89–2.06]

0.15

1.12 [0.69–1.81]

0.66

1.46 [0.88–2.42]

0.15

1.08 [0.60–1.97]

0.80

  > 8.18

1.03 [0.57–1.86]

0.92

1.33 [0.72–2.44]

0.36

1.17 [0.59–2.32]

0.65

1.43 [0.68–3.00]

0.35

1.15 [0.48–2.73]

0.76

  1. n/N = number of cases/total
  2. HR Hazard Ratio, CI Confidence Interval
  3. a Minimally adjusted Cox proportional hazard model: adjusted for age, center, sex, APOE, and education level
  4. b Multi-adjusted Cox proportional hazard model: adjusted for age, center, sex, APOE, education level, living alone, diabetes, depressive symptomatology, cardiovascular disease