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Table 1 Baseline characteristics and dementia incidence during the 8-year follow-up (n = 1550)

From: Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort

 Dementia status at the end of the follow-up 
 No dementia (n = 1433)Dementia (n = 117)
 n (%)n (%)HR (95%CI)aP valuea
Sex, female905 (63.2)80 (68.4)1.08 (0.73–1.60)0.71
Education level ≤ 5 years337 (23.5)33 (28.2)1.15 (0.76–1.75)0.50
APOE4 e4 carrier235 (16.4)29 (24.8)1.87 (1.23–2.85)0.004
Living alone591 (41.2)48 (41.0)0.71 (0.47–1.06)0.10
Diabetes141 (9.8)17 (14.5)1.69 (1.01–2.85)0.05
Hierarchical disability indicator
 Fully independent605 (42.2)34 (29.1)1 (Ref)
 Mild disability643 (44.9)49 (41.9)1.16 (0.73–1.83)0.54
 Moderate to severe disability185 (12.9)34 (29.1)2.55 (1.47–4.40)0.001
Depressive symptoms
 CES-D < 16 and no treatment1173 (81.9)80 (68.4)1 (Ref)
 CES-D 16–22 and no treatment82 (5.7)9 (7.7)1.84 (0.92–3.68)0.08
 CES-D ≥ 23 or treatment178 (12.4)28 (23.9)2.15 (1.39–3.34)0.001
Cardiovascular history**227 (15.8)28 (23.9)1.58 (1.02–2.44)0.04
Fractures in the past 2 or 3 years155 (10.9)11 (9.4)0.75 (0.40–1.40)0.36
  1. Notes: HR Hazard Ratio, CI Confidence Interval, CES-D Center for Epidemiologic Studies Depression Scale
  2. a Cox proportional hazard model adjusted for age, center, sex, APOE genotype, and educational level
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