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Table 1 Baseline characteristics and dementia incidence during the 8-year follow-up (n = 1550)

From: Physical activity types and risk of dementia in community-dwelling older people: the Three-City cohort

 

Dementia status at the end of the follow-up

 
 

No dementia (n = 1433)

Dementia (n = 117)

 

n (%)

n (%)

HR (95%CI)a

P valuea

Sex, female

905 (63.2)

80 (68.4)

1.08 (0.73–1.60)

0.71

Education level ≤ 5 years

337 (23.5)

33 (28.2)

1.15 (0.76–1.75)

0.50

APOE4 e4 carrier

235 (16.4)

29 (24.8)

1.87 (1.23–2.85)

0.004

Living alone

591 (41.2)

48 (41.0)

0.71 (0.47–1.06)

0.10

Diabetes

141 (9.8)

17 (14.5)

1.69 (1.01–2.85)

0.05

Hierarchical disability indicator

 Fully independent

605 (42.2)

34 (29.1)

1 (Ref)

 Mild disability

643 (44.9)

49 (41.9)

1.16 (0.73–1.83)

0.54

 Moderate to severe disability

185 (12.9)

34 (29.1)

2.55 (1.47–4.40)

0.001

Depressive symptoms

 CES-D < 16 and no treatment

1173 (81.9)

80 (68.4)

1 (Ref)

 CES-D 16–22 and no treatment

82 (5.7)

9 (7.7)

1.84 (0.92–3.68)

0.08

 CES-D ≥ 23 or treatment

178 (12.4)

28 (23.9)

2.15 (1.39–3.34)

0.001

Cardiovascular history**

227 (15.8)

28 (23.9)

1.58 (1.02–2.44)

0.04

Fractures in the past 2 or 3 years

155 (10.9)

11 (9.4)

0.75 (0.40–1.40)

0.36

  1. Notes: HR Hazard Ratio, CI Confidence Interval, CES-D Center for Epidemiologic Studies Depression Scale
  2. a Cox proportional hazard model adjusted for age, center, sex, APOE genotype, and educational level