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Table 6 Association between Baseline Slow Gait Speed and Falls at 18 Months in Mild to Moderate AD. Under all models, slow gait speed was significantly associated with falls (dependent variable) risk at 18 months. ADAS-Cog = Alzheimer Disease Assessment Scale – Cognitive Subsection

From: Gait speed, cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD

PredictorModel 1 Model 2 Model 3 
 IRR (95% CI)PIRR (95% CI)PIRR (95% CI)P
Baseline Slow Gait Speed3.18 (1.97–5.11)< 0.0013.27 (1.96–5.50)< 0.001*3.09 (1.82–5.22)< 0.001*
Baseline ADAS-Cog  0.95 (0.92–0.97)0.001*0.95 (0.92–0.98)0.001*
Age  1.07 (1.04–1.10)< 0.001*1.07 (1.03–1.10)< 0.001*
Gender (Female)  1.90 (1.15–3.11)0.012*1.60 (0.97–2.65)0.068
Study Arm  1.20 (0.78–1.83)0.4091.32 (0.85–2.06)0.218
Body Mass Index  0.98 (0.94, 1.03)0.4890.96 (0.92–1.01)0.149
Education (Years)  1.07 (1.01–1.12)0.021*1.10 (1.04–1.15)0.001*
Diagnosis Duration  1.02 (0.88–1.17)0.8160.96 (0.84–1.11)0.612
Total Comorbidities    0.97 (0.88–1.07)0.527
Diabetes Mellitus    1.73 (0.85–3.51)0.128
Arthritis    2.19 (1.19–4.04)0.012*
Total Medications    1.03 (0.95–1.12)0.490
Benzodiazepine Use    1.05 (1.04–3.64)0.036*
Antidepressant Use    0.67 (0.41–1.07)0.096
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