Gait speed, cognition and falls in people living with mild-to-moderate Alzheimer disease: data from NILVAD

BMC Geriatrics

Table 4 Association between Baseline Cognition (ADAS-Cog) and incident Slow Gait Speed at 18 Months in Mild to Moderate AD. Under all models, baseline cognition was significantly associated with incident slow gait speed (dependent). ADAS-Cog = Alzheimer Disease Assessment Scale – Cognitive Subsection

Predictor	Model 1		Model 2		Model 3
	OR (95% CI)	P	OR (95% CI)	P	OR (95% CI)	P
Baseline ADAS-Cog	1.04 (1.01, 1.07)	0.015*	1.04 (1.01–1.08)	0.009*	1.04 (1.01–1.08)	0.011*
Age			1.10 (1.05–1.15)	< 0.001*	1.10 (1.05–1.16)	< 0.001*
Gender (Female)			0.61 (0.32–1.18)	0.143	0.63 (0.32–1.24)	0.178
Study Arm			0.82 (0.44–1.54)	0.534	0.70 (0.37–1.36)	0.294
Body Mass Index			1.09 (1.01, 1.16)	0.023*	1.10 (1.02, 1.18)	0.014*
Education (Years)			1.08 (0.99–1.16)	0.076	1.08 (0.99–1.17)	0.064
Diagnosis Duration			1.07 (0.90–1.26)	0.443	1.07 (0.90–1.26)	0.466
Total Comorbidities					0.96 (0.82–1.11)	0.531
Diabetes Mellitus					0.41 (0.11–1.59)	0.195
Arthritis					0.54 (0.14–2.10)	0.373
Total Medications					1.06 (0.94–1.21)	0.330
Benzodiazepine Use					1.49 (0.55–4.01)	0.433
Antidepressant Use					0.99 (0.49–1.98)	0.989

ISSN: 1471-2318