Development and validation of a screening tool for early identification of bloodstream infection in older patients – a retrospective case-control study

Table 1 Learn Cohort Patient Characteristics

Parameter	Total (%)	Case (%)	Control (%)	p-value	OR	95% CI for OR
Number of patients	210	105 (50)	105 (50)	–	–	–
Sex (Male)	108 (51)	54 (51)	54 (51)	1.11	1.00	0.58–1.72
Mean Age on Date of Study Entry (Years) (± SD)	86 (± 4)	86 (± 4)	85 (± 4)	0.70	–	–
Hospital Location (Ward)	208 (99)	104 (99)	104 (99)	1.50	1.00	0.06–16.21
Median LOS (Days) at Study Entry (Range)	0.31 (0–27)	0.31 (0–27)	0.31 (0–27)	> 0.999	–	–
Neoplastic Disease	82 (39)	42 (40)	40 (38)	0.89	1.08	0.62–1.89
Diabetes Mellitus	56 (27)	29 (28)	27 (26)	0.88	1.10	0.60–2.03
Dementia	55 (26)	28 (27)	27 (26)	1.00	1.05	0.57–1.94
CHF	60 (29)	29 (28)	31 (30)	0.88	0.91	0.50–1.66
COPD	29 (14)	14 (13)	15 (14)	1.00	0.92	0.42–2.02
ESRD	11 (5)	8 (8)	3 (3)	0.21	2.80	0.72–10.89
Malnutrition	6 (3)	2 (2)	4 (4)	0.66	0.45	0.07–2.76
Antipyretic Use^a	62 (30)^b	37 (36)^b	25(24)	0.07	1.79	0.98–3.28
Corticosteroid Use^c	28 (13)	10 (10)	18 (17)	0.15	0.51	0.22–1.16
Survival	194 (92)	91 (87)	103 (98)	0.003	0.13	0.03–0.57

^aDefined as any antipyretic medication given on the day of patient data study entry date
^bMedication administration record to identify antipyretic use on day of patient study entry date was not found by Health Data Resources for two Case patients. Therefore, denominator used for Cases and Total in this analysis were 103 and 208, respectively
^cDefined as any corticosteroid medication given within 7 days of patient data study entry date

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