Table 2 Cox proportional hazards regression analyses for the risk of dementia among patients with lower urinary tract symptoms and different cumulative defined daily doses of therapeutic bladder anticholinergics

  < 28

 28–84

(0.70–1.05)

(0.73–1.06)

 85–336

(0.94–1.32)

(0.97–1.37)

  ≥ 337

(1.10–1.76)

(1.12–1.75)

Age (years)

(1.08–1.09)

(1.08–1.09)

 Male

 Female

(1.02–1.31)

(1.19–1.53)

Catastrophic illness certificate

(1.35–1.76)

(1.09–1.42)

 Diabetes mellitus

(1.04–1.46)

(0.96–1.37)

 Hyperlipidemia

(0.84–1.83)

(1.04–2.24)

 Hypertension

(1.03–1.41)

(0.82–1.13)

 CAD

(0.72–1.36)

(0.53–0.97)

 CVD

(1.89–3.21)

(1.46–2.52)

 Atrial fibrillation

(1.18–4.12)

(0.75–2.63)

Number of outpatient visits per year

(1.01–1.02)

(1.00–1.01)