Table 1 Characteristics of patients with lower urinary tract symptoms by categories of cumulative defined daily doses of therapeutic bladder anticholinergics
|  | Total (n = 16,412) | < 28 cDDDs (n = 13,681) | 28–84 cDDDs (n = 1285) | 85–336 cDDDs (n = 1024) | ≥337 cDDDs (n = 422) | P | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
n | (%) | n | (%) | n | (%) | n | (%) | n | (%) | Â | |
Baseline characteristics | |||||||||||
 Age (years), mean (SD) | 66.5 | (9.6) | 66.4 | (9.8) | 67.1 | (8.8) | 67.2 | (8.5) | 67.9 | (8.1) | < 0.001 |
  50–59 | 4346 | (26.5) | 3787 | (27.7) | 277 | (21.6) | 206 | (20.1) | 76 | (18.0) | < 0.001 |
  60–69 | 5421 | (33.0) | 4441 | (32.4) | 447 | (34.8) | 377 | (36.8) | 156 | (37.0) |  |
  70–79 | 5192 | (31.6) | 4173 | (30.5) | 482 | (37.5) | 377 | (36.8) | 160 | (37.9) |  |
   ≥ 80 | 1453 | (8.9) | 1280 | (9.4) | 79 | (6.1) | 64 | (6.3) | 30 | (7.1) |  |
Sex |  |  |  |  |  |  |  |  |  |  | < 0.001 |
 Male | 13,745 | (83.7) | 11,312 | (82.7) | 1130 | (87.9) | 919 | (89.7) | 384 | (91.0) |  |
 Female | 2667 | (16.3) | 2369 | (17.3) | 155 | (12.1) | 105 | (10.3) | 38 | (9.0) |  |
Catastrophic illness certificate | 2496 | (15.2) | 2094 | (15.3) | 181 | (14.1) | 142 | (13.9) | 79 | (18.7) | 0.078 |
Comorbidities | |||||||||||
 Diabetes mellitus | 1093 | (6.7) | 950 | (6.9) | 56 | (4.5) | 57 | (5.6) | 30 | (7.1) | 0.002 |
 Hyperlipidemia | 236 | (1.4) | 199 | (1.5) | 16 | (1.3) | 15 | (1.5) | 6 | (1.4) | 0.946 |
 Hypertension | 2019 | (12.3) | 1706 | (12.5) | 128 | (10.0) | 134 | (13.1) | 51 | (12.1) | 0.058 |
 CAD | 391 | (2.4) | 323 | (2.4) | 32 | (2.5) | 23 | (2.3) | 13 | (3.1) | 0.787 |
 CVD | 452 | (2.8) | 392 | (2.9) | 27 | (2.1) | 23 | (2.3) | 10 | (2.4) | 0.273 |
 Atrial fibrillation | 44 | (0.3) | 37 | (0.3) | 2 | (0.2) | 4 | (0.4) | 1 | (0.2) | 0.753 |
 Depression | 40 | (0.2) | 33 | (0.2) | 0 | (0.0) | 5 | (0.5) | 2 | (0.5) | 0.087 |
 TBI | 20 | (0.1) | 19 | (0.1) | 1 | (0.1) | 0 | (0.0) | 0 | (0.0) | 0.254 |
Follow-up characteristics | |||||||||||
 Number of outpatient visits per year, mean (SD) | 27.4 | (19.9) | 27.1 | (19.8) | 28.0 | (20.2) | 28.6 | (19.5) | 29.8 | (20.2) | 0.003 |
 Dementia | 1666 | (10.2) | 1372 | (10.0) | 115 | (8.9) | 118 | (11.5) | 61 | (14.4) | 0.005 |